502-05A

Human Bronchial Epithelial Cells: HBEpC, adult

• Synonym(e): HBEpC, HBEpC cells
• NACRES: NA.81
• UNSPSC Code: 41106514
• Biological source: human bronchi (normal surface epithelium)
• Growth mode: Adherent
• Morphology: epithelial
• Relevant disease(s): asthma; autoimmune diseases; cardiovascular diseases

Eigenschaften

• biological source: human bronchi (normal surface epithelium)
• packaging: pkg of 500,000 cells
• manufacturer/tradename: Cell Applications, Inc
• growth mode: Adherent
• karyotype: 2n = 46
• morphology: epithelial
• technique(s): cell culture | mammalian: suitable
• relevant disease(s): asthma; autoimmune diseases; cardiovascular diseases
• shipped in: dry ice
• storage temp.: −196°C

Beschreibung

General description

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HBEpC provide an excellent model system to study all aspects of epithelial function and disease, particularly those related to airway viral infections, as well as tissue repair mechanisms, signaling changes and potential treatments relevant to lung injuries, mechanical and oxidative stress, inflammation, pulmonary diseases and smoking.

When grown on inserts and provided with the liquid/air interface, HBEpC can differentiate into a pseudostriated epithelium and serve as a more physiological 3D tissue model for in vitro studies.

Application

epithelial function, tissue repair, cell signaling, lung injury treatment, mechanical and oxidative stress tests, cell differentiation, 3D tissue model, cytokine and growth factor production, apoptosis, cell adhesion molecules, cell permeability, pro-inflammatory signaling, viral fusion mechanisms, gene expression, library screening, mucin secretion

Biochem/physiol Actions

Bronchi

Preparation Note

• 1st passage, >500,000 cells in Cell Basal Medium containing 10% FBS & 10% DMSO
• Can be cultured at least 16 doublings

Please refer to the HBEpC Culture Protocol.

Other Notes

Cell Basal Medium containing 10% FBS & 10% DMSO

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Sicherheitshinweise

• Lagerklasse: 10 - Combustible liquids
• wgk: WGK 3
• flash_point_f: No data available
• flash_point_c: No data available