46985

Fluoreszein-5-thiosemicarbazid

suitable for fluorescence, ~80% (HPCE)

• Empirische Formel (Hill-System): C₂₁H₁₅N₃O₅S
• CAS-Nummer: 76863-28-0
• Molekulargewicht: 421.43
• NACRES: NA.32
• PubChem Substance ID: 329757284
• UNSPSC Code: 12352125
• MDL number: MFCD00155658

Eigenschaften

• assay: ~80% (HPCE)
• Quality Segment: 100
• form: solid
• solubility: DMF: soluble, H₂O: soluble
• fluorescence: λ_ex 492 nm; λ_em 516 nm in 0.1 M Tris pH 9.0
• suitability: suitable for fluorescence
• storage temp.: −20°C
• SMILES string: NNC(=S)Nc1ccc(c(c1)C(O)=O)C2=C3C=CC(=O)C=C3Oc4cc(O)ccc24
• InChI: 1S/C21H15N3O5S/c22-24-21(30)23-10-1-4-13(16(7-10)20(27)28)19-14-5-2-11(25)8-17(14)29-18-9-12(26)3-6-15(18)19/h1-9,25H,22H2,(H,27,28)(H2,23,24,30)
• InChI key: MEUCHQDLZYLNQY-UHFFFAOYSA-N

Beschreibung

General description

Fluorescein-5-thiosemicarbazide, also known as FTC, is a fluorescent probe.[1] The FTSC fluorescent spectra is like FITC, a preferred fluorescent tag for proteomics. The fluorescence spectral properties of FTSC-labeled vesicles obtained by reductive amination are fully compatible with the argon laser of fluorescent instruments.[2]

Application

Markierung von Funktionellen Gruppen an der Zelloberfläche (Glycophorine)[3]

Features and Benefits

Fluorescein-5-thiosemicarbazide has the following benefits -

• It displays strong fluorescence property.[2]
• Shows an intrinsic reactivity of the thiosemicarbazide group towards the aldehyde group.[2]

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)