T2695

Tetrandrin

analytical standard, for drug analysis

• Synonym(e): (1β)-6,6′,7,12-Tetramethoxy-2,2′-dimethylberbaman
• Empirische Formel (Hill-System): C₃₈H₄₂N₂O₆
• CAS-Nummer: 518-34-3
• Molekulargewicht: 622.75
• NACRES: NA.24
• PubChem Substance ID: 329826723
• UNSPSC Code: 41116107
• MDL number: MFCD08689909

Eigenschaften

• Quality Segment: 100
• assay: ≥90%
• form: solid
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): forensics and toxicology; pharmaceutical (small molecule); veterinary
• format: neat
• SMILES string: COc1ccc2C[C@@H]3N(C)CCc4cc(OC)c(OC)c(Oc5cc6[C@H](Cc7ccc(Oc1c2)cc7)N(C)CCc6cc5OC)c34
• InChI: 1S/C38H42N2O6/c1-39-15-13-25-20-32(42-4)34-22-28(25)29(39)17-23-7-10-27(11-8-23)45-33-19-24(9-12-31(33)41-3)18-30-36-26(14-16-40(30)2)21-35(43-5)37(44-6)38(36)46-34/h7-12,19-22,29-30H,13-18H2,1-6H3/t29-,30-/m0/s1
• InChI key: WVTKBKWTSCPRNU-KYJUHHDHSA-N

Beschreibung

General description

Tetrandrine (TET) is classified under the bisbenzylisoquinoline alkaloid family of compounds extracted from Stephania tetrandra S. Moore.

Application

Analgesic, antipyretic.
TET may be used as an analytical reference standard for the determination of TET in:

• Blood samples by online multidimensional solid phase extraction liquid chromatography coupled to tandem mass spectrometry (MD-SPE-LC-MS/MS) equipped with electrospray ionization (ESI) source and multiple reaction monitoring (MRM) detection.
• Rat plasma by ultra-high performance liquid chromatography (UHPLC) combined with MS/MS with MRM detection.
• Qi-Fang-Xi-Bi-Granules used in Chinese medicine by reversed phase HPLC equipped with ultraviolet (UV) detector.
• Fangji Huangqi Tang Chinese medicine by UHPLC coupled to triple quadrupole mass spectrometry (QqQ-MS) with MRM detection.

It may be used as an internal standard for the determination of hernandezine in:

• Rat plasma and tissues by UHPLC-MS/MS with MRM detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Sicherheitshinweise

• pictograms: GHS06
• signalword: Danger
• hcodes: H300
• pcodes: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 2 Oral
• Lagerklasse: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)