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S0252

Sulfobromphthalein Dinatriumsalz Hydrat

used to study hepatocyte transport functions

Synonym(e):

BSP, Bromsulfalein sodium disodium salt hydrate

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Ihnen/SKUVerfügbarkeitPreis
5 g
Warenkorb auf Verfügbarkeit prüfen
€ 566,00

Über diesen Artikel

Empirische Formel (Hill-System):
C20H8Br4Na2O10S2 · xH2O
CAS-Nummer:
Molekulargewicht:
838.00 (anhydrous basis)
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
200-761-0
MDL number:

€ 566,00


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Quality Segment

form

powder

composition

Water (by Karl Fischer): ≤ 8%

Sodium (Na) anhydrous: 4.6-5.8%

technique(s)

titration: suitable

color

white to light gray

solubility

water: 50 mg/mL (clear to very hazy)

λmax

575-581 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Na+].[Na+].[H]O[H].Oc1ccc(cc1S([O-])(=O)=O)C2(OC(=O)c3c(Br)c(Br)c(Br)c(Br)c23)c4ccc(O)c(c4)S([O-])(=O)=O

InChI

1S/C20H10Br4O10S2.2Na.H2O/c21-15-13-14(16(22)18(24)17(15)23)20(34-19(13)27,7-1-3-9(25)11(5-7)35(28,29)30)8-2-4-10(26)12(6-8)36(31,32)33;;;/h1-6,25-26H,(H,28,29,30)(H,31,32,33);;;1H2/q;2*+1;/p-2

InChI key

CDTNUNQQEUGDSD-UHFFFAOYSA-L

Application

Sulfobromophthalein disodium salt hydrate has been used as a positive control to study the interaction of 11-keto-β-boswellic acid (KBA) and 3-acetyl-11-keto-β-boswellic acid (AKBA) with organic anion transporter OATP1B3.

Biochem/physiol Actions

Sulfobromophthalein (BSP) is a high affinity organic ion substrate for organic anion transporting polypeptides (OATPs) and has been used as a substrate for multidrug resistance associated protein 2 (Mrp2). BSP is transported into hepatocytes by OATPs and, after conjugation to glutathione, is excreted into bile by Mrp2. It was found to inhibit the aldo-keto reductase ARK1C20.

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Dieser Artikel
B863086136771643
technique(s)

titration: suitable

technique(s)

titration: suitable

technique(s)

-

technique(s)

-

color

white to light gray

color

-

color

-

color

-

form

powder

form

powder

form

powder or crystals

form

crystals

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing

solubility

water: 50 mg/mL (clear to very hazy)

solubility

-

solubility

-

solubility

H2O: 0.5 M at 20 °C, clear, colorless

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200


pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Lagerklasse

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



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Questions

  1. Can S0252 be used to identify residual detergent in a bottle for a specific application?

    1 answer
    1. Bromothymol Blue is a pH indicator that changes color based on pH level and can be used to detect alkaline detergent residues inside a bottle. It changes color from yellow to blue at the transition pH of 7.6 if alkaline detergent residues are present. Additionally, the powdered form of the dye can be ordered, as well as other products sharing the same CAS number.

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