PHR8734

Methotrexat-verwandte Verbindung E

certified reference material, pharmaceutical secondary standard

• Synonym(e): 4-{[(2,4-Diaminopteridin-6-yl)-methyl]-(methyl)-amino}-benzoesäure -hemihydrochlorid
• Empirische Formel (Hill-System): C₁₅H₁₅N₇O₂ · 0.5HCl
• CAS-Nummer: 70844-48-3
• Molekulargewicht: 343.56
• UNSPSC Code: 41116107
• NACRES: NA.24
• eCl@ss: 25140904

Eigenschaften

• Quality Segment: 300
• grade: certified reference material, pharmaceutical secondary standard
• agency: traceable to USP (Reference Standard 1414058)
• API family: methotrexate
• CofA: current certificate can be downloaded
• packaging: pkg of 100 mg
• application(s): pharmaceutical
• SMILES string: Cl.N(Cc5nc6c(nc(nc6N)N)nc5)(C)c4ccc(cc4)C(=O)O.N(Cc2nc3c(nc(nc3N)N)nc2)(C)c1ccc(cc1)C(=O)O
• InChI: 1S/2C15H15N7O2.ClH/c2*1-22(10-4-2-8(3-5-10)14(23)24)7-9-6-18-13-11(19-9)12(16)20-15(17)21-13;/h2*2-6H,7H2,1H3,(H,23,24)(H4,16,17,18,20,21);1H
• InChI key: WWFYKUISNIJHNQ-UHFFFAOYSA-N

Beschreibung

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAA6959(changes by product) in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H317
• Sicherheitshinweise: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1
• Lagerklasse: 13 - Non Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable