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I0330000

Iopansäure

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

2-(3-Amino-2,4,6-triiodbenzyl)-buttersäure, 3-(3-Amino-2,4,6-triiodphenyl)-2-ethylpropansäure

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About This Item

Empirische Formel (Hill-System):
C11H12I3NO2
CAS-Nummer:
96-83-3
Molekulargewicht:
570.93
MDL-Nummer:
MFCD00038687
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329815308
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

iopanoic acid

Hersteller/Markenname

EDQM

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

O=C(O)C(CC)CC1=C(I)C(N)=C(I)C=C1I

InChI

1S/C11H12I3NO2/c1-2-5(11(16)17)3-6-7(12)4-8(13)10(15)9(6)14/h4-5H,2-3,15H2,1H3,(H,16,17)

InChIKey

OIRFJRBSRORBCM-UHFFFAOYSA-N

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Iopanoic acid EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Verpackung

Dieses Produkt wird, wie von der entsprechenden Pharmakopöe geliefert, angeboten. Die aktuellen Mengeneinheiten finden Sie im Referenzsubstanzen-Katalog der EDQM.

Sonstige Hinweise

Sales restrictions may apply.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H302

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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Analysenzertifikate (COA)

Lot/Batch Number

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A Colantuoni et al.
American journal of physiology. Heart and circulatory physiology, 288(4), H1931-H1936 (2004-12-04)
The aim of the present study was to assess the effects of topically applied triiodothyronine (T(3)) and thyroxine (T(4)) on the arterioles of hamster cheek pouch microcirculation in vivo. Microvessels were visualized using a fluorescent microscopy technique. Topical application of
Emmanuelle Havis et al.
The EMBO journal, 25(20), 4943-4951 (2006-09-29)
Thyroid hormone receptors generally activate transcription of target genes in the presence of thyroid hormone (T(3)) and repress their transcription in its absence. Here, we investigated the role of unliganded thyroid hormone receptor (TR) during vertebrate development using an amphibian
Fernando Lizcano et al.
Clinical and experimental pharmacology & physiology, 35(9), 1085-1090 (2008-05-29)
To investigate the effects of iopanoic acid (IA) and carbimazole on increased activity of the hypothalamic-pituitary-adrenal (HPA) axis in hyperthyroidism, we studied 14 women with hyperthyroidism caused by Graves' disease (n + 11) or toxic multinodular goitre (n + 3)
C S Bal et al.
The Journal of clinical endocrinology and metabolism, 90(12), 6536-6540 (2005-09-29)
Telepaque [iopanoic acid (IA)] is believed to rapidly ameliorate hyperthyroidism; however, it may preclude subsequent 131I therapy, possibly delaying it for several months. Our objective was to see how early patients, made euthyroid with Telepaque, can be treated with 131I
Joshua D Safer et al.
Thyroid : official journal of the American Thyroid Association, 19(2), 181-185 (2009-02-05)
Although cutaneous manifestations associated with thyroid dysfunction are classic, the potential for thyroid hormone or its antagonists to treat dermatological disease has not been explored with rigor. The predominant circulating thyroid hormone is the pro-hormone, thyroxine (T(4)). Skin, like many
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