E2503000

Etomidat

European Pharmacopoeia (EP) Reference Standard

• Synonym(e): (R)-1-(α-Methylbenzyl-imidazol-5-carbonsäure-ethylester
• Empirische Formel (Hill-System): C₁₄H₁₆N₂O₂
• CAS-Nummer: 33125-97-2
• Molekulargewicht: 244.29
• NACRES: NA.24
• PubChem Substance ID: 329799031
• UNSPSC Code: 41116107
• MDL number: MFCD00869295

Eigenschaften

• grade: pharmaceutical primary standard
• API family: etomidate
• manufacturer/tradename: EDQM
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: CCOC(=O)c1cncn1[C@H](C)c2ccccc2
• InChI: 1S/C14H16N2O2/c1-3-18-14(17)13-9-15-10-16(13)11(2)12-7-5-4-6-8-12/h4-11H,3H2,1-2H3/t11-/m1/s1
• InChI key: NPUKDXXFDDZOKR-LLVKDONJSA-N
• Gene Information: human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879)

Beschreibung

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Etomidate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Etomidate is a general anesthetic; potentiates GABA_A transmission

Etomidate is a general anesthetic; potentiates GABAA transmission. The possible neuroprotective effect of etomidate against streptozotocin-induced (STZ-induced) hyperglycaemia were investigated in the rat brain and spinal cord. Etomidate treatment demonstrated neuroprotective effect on the neuronal tissue against the diabetic oxidative damage

Packaging

Dieses Produkt wird, wie von der entsprechenden Pharmakopöe geliefert, angeboten. Die aktuellen Mengeneinheiten finden Sie im Referenzsubstanzen-Katalog der EDQM.

Other Notes

Sales restrictions may apply.

Sicherheitshinweise

• pictograms: GHS07,GHS09
• signalword: Warning
• hcodes: H302,H410
• pcodes: P273 - P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable