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C2174005

Cilazapril-Unreinheit D

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

(1S,9S)-9-{[(R)-1-Ethoxycarbonyl-3-phenylpropyl]-amino}-10- oxo-octahydro-6H-pyridazino[1,2a][1,2]diazepin-1-carbonsäure

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About This Item

Empirische Formel (Hill-System):
C22H31N3O5
CAS-Nummer:
Molekulargewicht:
417.50
UNSPSC-Code:
41116107
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

cilazapril

Hersteller/Markenname

EDQM

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Cilazapril impurity D EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Verpackung

Dieses Produkt wird, wie von der entsprechenden Pharmakopöe geliefert, angeboten. Die aktuellen Mengeneinheiten finden Sie im Referenzsubstanzen-Katalog der EDQM.

Sonstige Hinweise

Sales restrictions may apply.

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Milan R Radovanović et al.
Vojnosanitetski pregled, 66(11), 904-908 (2009-12-19)
Poisoning caused by drugs with cardiodepressive effects is an urgent condition in medicine which is associated with high mortality rate regardless of modern therapeutic methods. Accidental or intentional poisoning whit these drugs produces heart activity depression and cardiovascular collapse as
Izzet Hosgor et al.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 19(1), 101-105 (2008-01-09)
Impaired fibrinolysis is associated with thromboembolic complications in hypertensive patients. Cardiovascular morbidity/mortality rates have been reported high even after lowering the elevated blood pressure with antihypertensive drugs. We investigated the effects of clinically used dosages of cilazapril on the fibrinolytic
Spironolactone attenuates oxidative stress in patients with chronic kidney disease.
Marcin Renke et al.
Hypertension (Dallas, Tex. : 1979), 52(5), e132-e133 (2008-10-01)
Aleksander Skoczylas et al.
Endokrynologia Polska, 61(1), 21-27 (2010-03-06)
Ghrelin is a polypeptide hormone secreted mainly by the stomach cells, stimulating food intake and growth hormone release. Decreased plasma ghrelin concentration was found in obese subjects. Clinical and experimental data suggest that ghrelin also exerts a blood pressure lowering
Nikola Radović et al.
Croatian medical journal, 49(5), 600-607 (2008-10-18)
To investigate the effects of angiotensin-converting enzyme inhibitor (cilazapril) and angiotensin II type I receptor antagonist (losartan) on tubular and interstitial cell apoptosis and caspase-3 activity in rats with obstructive nephropathy after unilateral ureteral obstruction. Rats with unilateral obstructive nephropathy

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