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BP809

Cisplatin

British Pharmacopoeia (BP) Reference Standard

Synonym(e):

cis-Diamminplatin(II)-dichlorid, cis-Dichlordiamminplatin(II), cis-Platin(II)-diammin-dichlorid, Cisplatin

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Über diesen Artikel

Lineare Formel:
Pt(NH3)2Cl2
CAS-Nummer:
Molekulargewicht:
300.05
UNSPSC Code:
41116107
NACRES:
NA.24
EC Number:
239-733-8
MDL number:

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InChI key

LXZZYRPGZAFOLE-UHFFFAOYSA-L

InChI

1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2

SMILES string

N.N.Cl[Pt]Cl

grade

pharmaceutical primary standard

API family

cisplatin

form

solid

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

mp

270 °C (lit.)

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

storage temp.

2-8°C

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Dieser Artikel
C22100001134357232120
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BP809

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Cisplatin European Pharmacopoeia (EP) Reference Standard

C2210000

Cisplatin

Cisplatin United States Pharmacopeia (USP) Reference Standard

USP

1134357

Cisplatin

manufacturer/tradename

BP

manufacturer/tradename

EDQM

manufacturer/tradename

USP

manufacturer/tradename

Calbiochem®

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

-

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

-

application(s)

pharmaceutical
pharmaceutical small molecule

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

-

format

neat

format

neat

format

neat

format

-

form

solid

form

-

form

-

form

solid

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Cisplatin BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Cisplatin Injection
  • Biochem/physiol Actions

    Wirksames Platin-basiertes Antineoplastikum. Bildet mit dem DNA-Dinukleotid d(pGpG) zytotoxischen Addukte, induziert Intrastrang-Quervernetzung.

    Packaging

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Other Notes

    Sales restrictions may apply.

    pictograms

    Skull and crossbonesHealth hazard

    signalword

    Danger

    target_organs

    Respiratory system

    Lagerklasse

    6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

    wgk

    WGK 3

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable

    Hazard Classifications

    Acute Tox. 2 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 1B - Repr. 1B - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3


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    Journal of cellular biochemistry, 121(5-6), 3256-3265 (2020-01-07)
    Aberrant activation of the Hedgehog (Hh)/Gli pathway contributes to the tumorigenesis of several human cancers, including ovarian cancers. We investigated the function of SMO on cell growth, drug resistance, and invasive ability in A2780/DDP cells. Moreover, we also tested the
    Ruiqian Li et al.
    International urology and nephrology, 52(1), 187-196 (2019-12-13)
    Cisplatin could result in a wide range of kidney injuries. During the pathogenetic process, the excessive generation of reactive oxygen species (ROS) induced by cisplatin has been regarded as the initial and critical role, by which DNA damage and cell
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    Oxidative stress is associated with many acute and chronic inflammatory diseases, yet limited treatment is currently available clinically. The development of enzyme-mimicking nanomaterials (nanozymes) with good reactive oxygen species (ROS) scavenging ability and biocompatibility is a promising way for the

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