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BP809

Cisplatin

British Pharmacopoeia (BP) Reference Standard

Synonym(e):

cis-Diamminplatin(II)-dichlorid, cis-Dichlordiamminplatin(II), cis-Platin(II)-diammin-dichlorid, Cisplatin

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Über diesen Artikel

Lineare Formel:
Pt(NH3)2Cl2
CAS-Nummer:
Molekulargewicht:
300.05
UNSPSC Code:
41116107
NACRES:
NA.24
EC Number:
239-733-8
MDL number:
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grade

pharmaceutical primary standard

API family

cisplatin

form

solid

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

mp

270 °C (lit.)

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

storage temp.

2-8°C

SMILES string

N.N.Cl[Pt]Cl

InChI

1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2

InChI key

LXZZYRPGZAFOLE-UHFFFAOYSA-L

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Cisplatin BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Cisplatin Injection
  • Biochem/physiol Actions

    Wirksames Platin-basiertes Antineoplastikum. Bildet mit dem DNA-Dinukleotid d(pGpG) zytotoxischen Addukte, induziert Intrastrang-Quervernetzung.

    Packaging

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Other Notes

    Sales restrictions may apply.

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    USP

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    manufacturer/tradename

    BP

    manufacturer/tradename

    USP

    manufacturer/tradename

    Calbiochem®

    manufacturer/tradename

    -

    grade

    pharmaceutical primary standard

    grade

    pharmaceutical primary standard

    grade

    -

    grade

    -

    form

    solid

    form

    -

    form

    solid

    form

    -

    format

    neat

    format

    neat

    format

    -

    format

    -

    shelf life

    limited shelf life, expiry date on the label

    shelf life

    -

    shelf life

    -

    shelf life

    -

    application(s)

    pharmaceutical
    pharmaceutical small molecule

    application(s)

    pharmaceutical (small molecule)

    application(s)

    -

    application(s)

    -


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    pictograms

    Skull and crossbonesHealth hazard

    signalword

    Danger

    target_organs

    Respiratory system

    Lagerklasse

    6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

    wgk

    WGK 3

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable

    Hazard Classifications

    Acute Tox. 2 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 1B - Repr. 1B - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3



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    Analysenzertifikate (COA)

    Lot/Batch Number

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    Ruiqian Li et al.
    International urology and nephrology, 52(1), 187-196 (2019-12-13)
    Cisplatin could result in a wide range of kidney injuries. During the pathogenetic process, the excessive generation of reactive oxygen species (ROS) induced by cisplatin has been regarded as the initial and critical role, by which DNA damage and cell
    Xiaochen Wang et al.
    Stem cells international, 2020, 8877577-8877577 (2020-09-05)
    Esophageal squamous cell carcinoma (ESCC) is a frequent malignant tumor with low 5-year overall survival. Targeting ESCC tumor-initiating cells (TICs) may provide a new research avenue to achieve better therapeutic effects of ESCC. However, the identity and characteristics of ESCC



    Global Trade Item Number

    SKUGTIN
    BP80904061835275700

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