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BP653

Famotidin

British Pharmacopoeia (BP) Reference Standard

Synonym(e):

N′-(Aminosulfonyl)-3-{[2-(diaminomethylenamino)-4-thiazolyl]-methylthio}-propanamidin

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Über diesen Artikel

Empirische Formel (Hill-System):
C8H15N7O2S3
CAS-Nummer:
Molekulargewicht:
337.45
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
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Unterstützung erhalten


grade

pharmaceutical primary standard

agency

BP

API family

famotidine

form

solid

shelf life

limited shelf life, expiry date on the label

packaging

pkg of 100 mg

manufacturer/tradename

BP

storage condition

OK to freeze

color

white

mp

162-165 °C

solubility

water: insoluble

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

shipped in

ambient

storage temp.

2-8°C

SMILES string

N\C(N)=N\c1nc(CSCCC(=N)NS(N)(=O)=O)cs1

InChI

1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)

InChI key

XUFQPHANEAPEMJ-UHFFFAOYSA-N

Gene Information

human ... HRH2(3274)

General description

Famotidine is a hydrophilic, cationic, histamine H2 receptor antagonist drug that effectively inhibits gastric acid secretion in humans.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Famotidine BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Famotidine Tablets
  • Biochem/physiol Actions

    H2 Histamin-Rezeptorantagonist; Antiulcusmittel

    Packaging

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Other Notes

    Sales restrictions may apply.

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    Famotidine United States Pharmacopeia (USP) Reference Standard

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    1269200

    Famotidine

    manufacturer/tradename

    BP

    manufacturer/tradename

    EDQM

    manufacturer/tradename

    USP

    manufacturer/tradename

    -

    grade

    pharmaceutical primary standard

    grade

    pharmaceutical primary standard

    grade

    pharmaceutical primary standard

    grade

    certified reference material, pharmaceutical secondary standard

    form

    solid

    form

    solid

    form

    powder

    form

    -

    application(s)

    pharmaceutical
    pharmaceutical small molecule

    application(s)

    pharmaceutical (small molecule)

    application(s)

    pharmaceutical (small molecule)

    application(s)

    pharmaceutical (small molecule)

    format

    neat

    format

    neat

    format

    neat

    format

    neat

    shelf life

    limited shelf life, expiry date on the label

    shelf life

    -

    shelf life

    -

    shelf life

    -


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    Lagerklasse

    11 - Combustible Solids

    wgk

    WGK 2

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable



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    Analysenzertifikate (COA)

    Lot/Batch Number

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    Famotidine
    British Pharmacopeia
    British Pharmacopoeia, 29(1-2), 247-254 (2020)
    Determination of cimetidine, famotidine, and ranitidine hydrochloride in the presence of their sulfoxide derivatives in pure and dosage forms by high-performance thin-layer chromatography and scanning densitometry
    Kelani KM, et al.
    Journal of AOAC (Association of Official Analytical Chemists) International, 85(5), 1015-1020 (2002)
    Determination of famotidine in acid reduction tablets by HPTLC and videodensitometry of fluorescence quenched zones
    Campbell AN and Sherma J
    Journal of Liquid Chromatography and Related Technologies, 26(16), 2719-2727 (2003)



    Global Trade Item Number

    SKUGTIN
    BP65304061835278336