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2-(2-Methyl-5-nitro-1H-imidazol-1-yl)-essigsäure

analytical standard

Synonym(e):

1-Carboxymethylmetronidazol, 2-Methyl-5-nitroimidazol-1-essigsäure

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About This Item

Empirische Formel (Hill-System):
C6H7N3O4
CAS-Nummer:
1010-93-1
Molekulargewicht:
185.14
Beilstein:
613770
MDL-Nummer:
MFCD01721819
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329764410
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

100

Assay

≥97.5% (GC)

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Verunreinigungen

≤0.5% water

Anwendung(en)

forensics and toxicology
pharmaceutical (small molecule)

Format

neat

SMILES String

O=C(O)CN1C(C)=NC=C1[N+]([O-])=O

InChI

1S/C6H7N3O4/c1-4-7-2-5(9(12)13)8(4)3-6(10)11/h2H,3H2,1H3,(H,10,11)

InChIKey

RVEGZXNRNWUYKI-UHFFFAOYSA-N

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Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H319

Gefahreneinstufungen

Eye Irrit. 2

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
BCCG1281
BCCF1730
BCBX5230
BCBQ9694V
BCBL3638V

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B Fredricsson et al.
Gynecologic and obstetric investigation, 24(3), 200-207 (1987-01-01)
Metronidazole kinetics was studied in 5 healthy women after a single dose given intravenously, orally or vaginally, 500, 400 and 500 mg, respectively. Serum levels of the drug and of its hydroxy and acid metabolites were assessed. The results after
R A Gibson et al.
Clinical chemistry, 30(5), 784-787 (1984-05-01)
Metronidazole and its known metabolites in plasma can be rapidly separated by a "high-pressure" liquid-chromatographic method that can also be adapted for rapid determination of tinidazole. Samples deproteinized with trichloroacetic acid (50 g/L final concentration) undergo isocratic separation on a
B Salvesen et al.
Scandinavian journal of gastroenterology. Supplement, 91, 31-43 (1984-01-01)
A high-performance liquid chromatography (HPLC) method for the assay of metronidazole and its 2-hydroxymethyl metabolite in sera was compared with a microbiological method, an agar well diffusion technique with Clostridium perfringens as indicator strain. The HPLC technique involves separation of
O Eradiri et al.
Biopharmaceutics & drug disposition, 8(3), 249-259 (1987-05-01)
The pharmacokinetics of metronidazole (MTZ) were studied in six Crohn's disease patients after multiple oral daily doses of 250, 500, 750, and 1000 mg day-1. Pharmacokinetic indices were found to be independent of the dose administered. The half-life, volume of
D R Guay et al.
Antimicrobial agents and chemotherapy, 25(3), 306-310 (1984-03-01)
The pharmacokinetics of metronidazole, its biologically active alcohol metabolite, and its inactive acid metabolite were studied in five noninfected patients undergoing continuous ambulatory peritoneal dialysis and five patients undergoing hemodialysis. The latter were studied on off-dialysis days as a control
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