41171

4-Hydroxyöstradiol

analytical standard

• Synonym(e): 1,3,5(10)-Oestratrien-3,4,17β-triol
• Empirische Formel (Hill-System): C₁₈H₂₄O₃
• CAS-Nummer: 5976-61-4
• Molekulargewicht: 288.38
• MDL-Nummer: MFCD00063335
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329756068
• NACRES: NA.24

Eigenschaften

• Qualität: analytical standard
• Qualitätsniveau: 100
• Assay: ≥95.0% (HPLC)
• Haltbarkeit: limited shelf life, expiry date on the label
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• Anwendung(en): pharmaceutical
• Format: neat
• Lagertemp.: −20°C
• SMILES String: [H][C@]12CC[C@]3(C)[C@@H](O)CC[C@@]3([H])[C@]1([H])CCc4c(O)c(O)ccc24
• InChI: 1S/C18H24O3/c1-18-9-8-11-10-4-6-15(19)17(21)13(10)3-2-12(11)14(18)5-7-16(18)20/h4,6,11-12,14,16,19-21H,2-3,5,7-9H2,1H3/t11-,12-,14+,16+,18+/m1/s1
• InChIKey: QOZFCKXEVSGWGS-ZHIYBZGJSA-N

Beschreibung

Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem./physiol. Wirkung

4-Hydroxyestradiol, an metabolite of estradiol, forms adducts with adenine (N³) and guanine (N⁷) by depurinating sites in DNA of cultured human breast epithelial cells. This effect may play an important role in malignant transformation of these cells.

Hinweis zur Analyse

LC-MS identity conforms

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Warning
• H-Sätze: H351
• P-Sätze: P281
• Gefahreneinstufungen: Carc. 2
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable