34089

Fosfomycin Natrium

VETRANAL^®, analytical standard

• Synonym(e): Phosphomycin Dinatriumsalz, (−)-(1R,2S)-(1,2-Epoxypropyl)-phosphonsäure, Fosfomycin, Phosphomycin
• Empirische Formel (Hill-System): C₃H₅Na₂O₄P
• Molekulargewicht: 182.02
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329754806
• EC Number: 247-409-2
• Beilstein/REAXYS Number: 4604425
• MDL number: MFCD22741288

Eigenschaften

• grade: analytical standard
• Quality Segment: 100
• product line: VETRANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): clinical testing
• format: neat
• storage temp.: 2-8°C
• SMILES string: [Na+].[Na+].C[C@@H]1O[C@@H]1P([O-])([O-])=O
• InChI: 1S/C3H7O4P.2Na/c1-2-3(7-2)8(4,5)6;;/h2-3H,1H3,(H2,4,5,6);;/q;2*+1/p-2/t2-,3+;;/m0../s1
• InChI key: QZIQJIKUVJMTDG-JSTPYPERSA-L

Beschreibung

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Antibiotikum, das in der Niere und Blase konzentriert ist; verringert die Nephrotoxizität und Ototoxizität von platinhaltigen Antitumormitteln. Fosfomycin ist ein Phosphoenolpyruvatanalogon, das UDP-GlcNAc-Enolpyruvyltransferase (MurA), ein Enzym, das an der Biosynthese der Bakterienzellwand beteiligt ist, irreversibel hemmt. Folglich wird die Produktion von N-Acetylmuraminsäure, einem essenziellen Bestandteil der Peptidoglykanzellwand, gehemmt.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)