125660

Leucomalachitgrün

powder

• Synonym(e): 4,4′-Benzyliden-bis-(N,N-dimethylanilin)
• Lineare Formel: C₆H₅CH[C₆H₄N(CH₃)₂]₂
• CAS-Nummer: 129-73-7
• Molekulargewicht: 330.47
• UNSPSC Code: 12171500
• NACRES: NA.47
• PubChem Substance ID: 24847677
• EC Number: 204-961-9
• Beilstein/REAXYS Number: 2140506
• MDL number: MFCD00008315

Eigenschaften

• form: powder
• Quality Segment: 100
• technique(s): microbe id | staining: suitable
• mp: 100-102 °C (lit.)
• λmax: 623 nm
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: room temp
• SMILES string: CN(C)c1ccc(cc1)C(c2ccccc2)c3ccc(cc3)N(C)C
• InChI: 1S/C23H26N2/c1-24(2)21-14-10-19(11-15-21)23(18-8-6-5-7-9-18)20-12-16-22(17-13-20)25(3)4/h5-17,23H,1-4H3
• InChI key: WZKXBGJNNCGHIC-UHFFFAOYSA-N

Beschreibung

Application

Leucomalachite green has been used as a reagent in presumptive tests which are used to detect invisible blood stains.

Biochem/physiol Actions

Leucomalachite green (LMG) is a chief metabolite of malachite green, a triphenylmethane dye that has been used generally as an antifungal drug in the fish industry. DNA adducts formed in livers of rats fed with leucomalachite green have been observed with little mutagenic or carcinogenic effect. LMG is one of the most commonly used reagents for presumptive blood test. It gives a characteristic green color in the presence of blood. LMG destroys DNA in the blood, therefore, the chances of DNA recovery and amplification is reduced or eliminated.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07,GHS09
• Signalwort: Warning
• Gefahrencodes: H302,H341,H351,H410
• Sicherheitshinweise: P202 - P264 - P273 - P280 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Muta. 2
• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): dust mask type N95 (US), Eyeshields, Gloves