MAB5280X

Anti-Tyrosine Hydroxylase Antibody, clone 2/40/15, Alexa Fluor^™ 488

clone 2/40/15, Chemicon^®, from mouse

• Synonym(e): Anti-DYT14, Anti-DYT14|, Anti-DYT5b, Anti-TYH
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 100
• Konjugat: ALEXA FLUOR^™ 488
• Antikörperform: purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: 2/40/15, monoclonal
• Speziesreaktivität: rat, bovine, quail, chicken
• Hersteller/Markenname: Chemicon^®
• Methode(n): immunohistochemistry: suitable
• Isotyp: IgG2a
• NCBI-Hinterlegungsnummer: NM_000360.3; NM_199292.2; NM_199293.2
• UniProt-Hinterlegungsnummer: P07101
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: rat ... Th(25085)

Beschreibung

Spezifität

Tyrosine hydroxylase (TH) catalyzes the rate-determining initial step in the biosynthesis of catecholamines such as dopamine, noradrenaline and adrenaline. Therefore the antibody is used to stain dopaminergeous and adrenergeous neurons as well as the chromaffine tissue of the adrenal medulla. Cell lines such as the PC 12 line, which is derived from a rat pheochromocytoma also, show positive reactions. In immunoblots of adrenal medulla tissue, the antibody recognizes a single protein band in the molecular weight range of 56 - 60 kD.

Immunogen

Purified tyrosine hydroxylase (EC 1.14.16.2) from a rat pheochromocytoma (2).

Anwendung

Research Category
Neurowissenschaft

Research Sub Category
Neurotransmitter & Rezeptoren

Neuronen- & Gliamarker

Anti-Tyrosine Hydroxylase Antibody, clone 2/40/15, Alexa Fluor 488 is an antibody against Tyrosine Hydroxylase for use in IH.

Immunohistochemistry

Optimal working dilutions must be determined by end user.

Physikalische Form

Purified immunoglobulin conjugated to Alexa Fluor^™ 488. Liquid in Phosphate buffer with 15 mg/mL BSA as a stabilizer and 0.1% sodium azide.

Lagerung und Haltbarkeit

Maintain at 2-8°C in undiluted aliquots in the dark for up to 6 months after date of receipt.

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

ALEXA FLUOR is a trademark of Life Technologies

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Alexa Fluor^™ is a registered trademark of Molecular Probes, Inc.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable