MAB4315

Anti-STRO-1 Antibody, clone STRO-1

ascites fluid, clone STRO-1, Chemicon^®

• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Clone: STRO-1, monoclonal
• Species reactivity: human, primate
• Application: FACS, IF
• Citations: 21

Eigenschaften

• biological source: mouse
• Quality Segment: 100
• antibody form: ascites fluid
• antibody product type: primary antibodies
• clone: STRO-1, monoclonal
• species reactivity: human, primate
• manufacturer/tradename: Chemicon^®
• technique(s): flow cytometry: suitable, immunofluorescence: suitable
• input: sample type mesenchymal stem cell(s)
• isotype: IgM
• shipped in: dry ice
• target post-translational modification: unmodified

Beschreibung

General description

STRO-1 is a cell surface protein expressed by bone marrow stromal cells and erythroid precursors. The frequency of colony forming units fibroblasts (CFU-F) was enriched 100-fold in the STRO-1+/Glycophorin A- population from bone marrow cells. The subset of marrow cells that expresses the STRO-1 antigen is capable of differentiating into multiple mesenchymal lineages including hematopoiesis-supportive stromal cells with a vascular smooth muscle-like phenotype, adipocytes, osteoblasts, and chondrocytes.

Immunogen

CD34⁺ bone marrow cells

Application

Detect STRO-1 using this Anti-STRO-1 Antibody, clone STRO-1 validated for use in FC & IF.

Biochem/physiol Actions

Recognizes a cell surface antigen expressed by bone marrow stromal cells and stromal precursors. STRO-1 binds to approximately 10% of bone marrow mononuclear cells, greater than 95% of which are nucleated erythroid precursors.

Analysis Note

Control
Bone marrow cultures

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklasse: 10 - Combustible liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable