FCMAB182F

Milli-Mark^® Anti-CD15-FITC Antibody, clone C3D-1

clone C3D-1, Milli-Mark^®, from mouse

• Synonym(e): Alpha-(1,3)-fucosyltransferase, Galactoside 3-L-fucosyltransferase, Fucosyltransferase 4, Fucosyltransferase IV, FucT-IV, Fuc-TIV, ELAM-1 ligand fucosyltransferase
• UNSPSC Code: 12352203
• NACRES: NA.44
• eCl@ss: 32160702
• Conjugate: FITC conjugate
• Clone: C3D-1, monoclonal
• Application: FACS
• Citations: 2

Eigenschaften

• biological source: mouse
• Quality Segment: 100
• conjugate: FITC conjugate
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: C3D-1, monoclonal
• species reactivity: human
• manufacturer/tradename: Milli-Mark^®
• technique(s): flow cytometry: suitable
• isotype: IgMκ
• NCBI accession no.: NP_002024.1
• UniProt accession no.: P22083
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... FUT4(2526)

Beschreibung

General description

CD15 is a carbohydrate antigen carried by both glycoproteins and glycoliplds. The structure of the antigen was determined to be Galb1→4[Fuca1→3]GIcNACb1→3Galb1→R. CD15 serves as a ligand for selectins and might also be involved in cell adhesion through a direct Lewis X-Lewis X interaction. CD15 is expressed mainly on mature granulocytes and monocytes but also on immature bone marrow cells (Kannagi, 1997).
Anti-CD15, C3D-1, was included in the Sixth International Workshop and Conference on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with CD15 (Kannagi, 1997).

Immunogen

Purified human neutrophils

Application

This Milli-Mark Anti-CD15-FITC Antibody, clone C3D-1 is validated for use in FC for the detection of CD15.

Biochem/physiol Actions

Antibody recognizes Human CD15 antigen.

Physical form

Activated Sepharose

Purified Mouse monoclonal IgM conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

Analysis Note

Evaluated by flow cytometry using human PBMCs

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklasse: 12 - Non Combustible Liquids
• wgk: WGK 2