9490-OP

Polysorbat 80

OmniPur^®

• Synonym(e): TWEEN^® 80, POE (20) Sorbitanmonooleat, Polyethylenglycolsorbitanmonooleat, Polyoxyethylen-Sorbitan-Monooleat, Polysorbat 80
• CAS-Nummer: 9005-65-6
• UNSPSC Code: 12161902
• NACRES: NA.28
• MDL number: MFCD00082107

Eigenschaften

• Quality Segment: 100
• form: viscous liquid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: gold-yellow
• shipped in: ambient
• SMILES string: CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO
• InChI: 1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+
• InChI key: RGPBUVUVZKQNHD-MDZDMXLPSA-N

Beschreibung

General description

Non-ionic detergent suited for solubilization of membrane proteins, enzymology, analytical, and diagnostic, work as well as chromatography and electrophoresis. Molecular Biology Grade.

DNAse: none detected
Heavy metals (as Pb): ≤0.001%
Hydroxyl number: 65-80
Residue after ignition: ≤0.25%
Moisture (H₂O): ≤3%
Protease: none detected
RNAse: none detected





Intended for laboratory and manufacturing use only. Not for drug, food, or household use.

Application

• Surfactants′ Interplay with Biofilm Development in Staphylococcus and Candida.: This study explores how surfactants, including Polysorbate 80, influence biofilm development in Staphylococcus and Candida species. The findings highlight the critical role of surfactants in modulating biofilm formation, which has implications for developing new therapeutic strategies against biofilm-associated infections. (Aonofriesei, 2024).


• Stress-mediated polysorbate 20 degradation and its potential impact on therapeutic proteins.: This article examines the degradation of Polysorbate 20 under stress conditions and its effects on therapeutic proteins. While primarily focusing on Polysorbate 20, the insights are relevant for understanding the stability and formulation challenges of similar surfactants like Polysorbate 80 in pharmaceutical applications. (Aryal et al., 2024).


• Dissecting the toxicological profile of polysorbate 80 (PS80): comparative analysis of constituent variability and biological impact using a zebrafish model.: This comprehensive study evaluates the toxicological effects of Polysorbate 80 using a zebrafish model, providing detailed insights into its safety profile and biological impact, which are crucial for its use in pharmaceuticals and other applications. (Wang et al., 2024).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

OMNIPUR is a registered trademark of Merck KGaA, Darmstadt, Germany

TWEEN is a registered trademark of Croda International PLC

Disclaimer

Toxicity: Irritant (B)

Sicherheitshinweise

• Lagerklasse: 10 - Combustible liquids
• Flammpunkt (°F): >482.0 °F - Cleveland open cup
• Flammpunkt (°C): > 250 °C - Cleveland open cup