8.52413

Fmoc-Cys(methylcarboxamide)-OH

for peptide synthesis, Novabiochem^®

• Synonym(e): Fmoc-Cys(methylcarboxamide)-OH, N-α-Fmoc-S-methylcarboxamide-L-cysteine
• UNSPSC Code: 12352111
• NACRES: NA.22
• eCl@ss: 32150917

Eigenschaften

• Produktname: Fmoc-Cys(methylcarboxamide)-OH, Novabiochem^®
• Quality Segment: 200
• product line: Novabiochem^®
• form: powder
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• application(s): peptide synthesis
• functional group: thiol
• storage temp.: 15-25°C

Beschreibung

General description

A novel derivative for the introduction of carboxamidomethyl (Cam) modified cysteine residues by direct Fmoc SPPS. Cys(Cam) containing peptides are required as standards for MS quantitation of proteins.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Fmoc SPPS of Cysteine-Containing Peptides

Application

Fmoc-Cys(methylcarboxamide)-OH has been used as a building block in the synthesis of peptide-acridine conjugates that target RNA.

Analysis Note

Color (visual): white to off white
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.0 % (a/a)
Purity (HPLC): ≥ 98.0 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Solubility (1 mmole in 2 ml DMF): clearly soluble
Ethyl acetate (HS-GC): ≤ 0.5 %
Acetate (IC): ≤ 0.1 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable