8.52222

Fmoc-Ala-OPfp

Novabiochem^®

• Synonym(e): Fmoc-Ala-OPfp, N-α-Fmoc-L-alanine pentafluorophenyl ester
• Empirische Formel (Hill-System): C₂₄H₁₆F₅NO₄
• CAS-Nummer: 86060-86-8
• Molekulargewicht: 477.38
• UNSPSC Code: 12352209
• NACRES: NA.22
• MDL number: MFCD00065612

Eigenschaften

• Quality Segment: 200
• product line: Novabiochem^®
• assay: ≥98.0% (HPLC)
• form: powder
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• mp: 170-185 °C
• application(s): peptide synthesis
• functional group: Fmoc
• storage temp.: 15-25°C
• SMILES string: Fc1c(c(c(c(c1F)F)OC(=O)[C@@H](NC(=O)OCC2c3c(cccc3)c4c2cccc4)C)F)F
• InChI: 1S/C24H16F5NO4/c1-11(23(31)34-22-20(28)18(26)17(25)19(27)21(22)29)30-24(32)33-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,11,16H,10H2,1H3,(H,30,32)/t11-/m0/s1
• InChI key: CJXZXBGKOSXBFR-NSHDSACASA-N

Beschreibung

General description

Pre-formed pentafluorophenyl ester for coupling of alanine amino-acid residues by Fmoc SPPS. Use enables bromophenol blue monitoring of amide bond formation.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in chloroform): -25.0 - -20.0 °
DCU (DC (0003)): ≤ 2 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (0,5 mmole in 3 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Other Notes

Replaces: 04-12-1500

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H315
• pcodes: P264 - P280 - P302 + P352 - P332 + P313 - P362 + P364
• Hazard Classifications: Skin Irrit. 2
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3