8.52210

Fmoc-Phe(4-Cl)-OH

Novabiochem^®

• Synonym(e): Fmoc-Phe(4-Cl)-OH, N-α-Fmoc-4-chloro-L-phenylalanine
• Empirische Formel (Hill-System): C₂₄H₂₀ClNO₄
• CAS-Nummer: 175453-08-4
• Molekulargewicht: 421.87
• UNSPSC Code: 12352209
• NACRES: NA.22
• MDL number: MFCD00080281

Eigenschaften

• Quality Segment: 200
• product line: Novabiochem^®
• assay: ≥95.0% (acidimetric), ≥98% (TLC), ≥98.0% (HPLC)
• form: powder
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• mp: 138 °C
• application(s): peptide synthesis
• functional group: chloro
• storage temp.: 2-30°C
• SMILES string: Clc1ccc(cc1)C[C@H](NC(=O)OCC2c3c(cccc3)c4c2cccc4)C(=O)O
• InChI: 1S/C24H20ClNO4/c25-16-11-9-15(10-12-16)13-22(23(27)28)26-24(29)30-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,26,29)(H,27,28)/t22-/m0/s1
• InChI key: CQPNKLNINBUUOM-QFIPXVFZSA-N

Beschreibung

General description

Standard building block for introduction of 4-chlorophenylalanine residues by Fmoc SPPS.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(157B)): ≥ 98 %
Purity (TLC(CMA2)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 95.0 %
Water (K. F.): ≤ 3.0 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Other Notes

Replaces: 04-12-1096

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable