8.41636

2-Aminoethyldiphenyl borate

for synthesis

• Synonym(e): 2-Aminoethyldiphenyl borate, Diphenylboric acid-2-aminoethyl ester
• Empirische Formel (Hill-System): C₁₄H₁₆BNO
• CAS-Nummer: 524-95-8
• Molekulargewicht: 225.09
• UNSPSC Code: 12352116
• EC Index Number: 208-366-5
• NACRES: NA.22
• MDL number: MFCD00014823
• Form: powder

Eigenschaften

• Quality Segment: 200
• form: powder
• mp: 189-194 °C
• SMILES string: B(OCCN)(c2ccccc2)c1ccccc1
• InChI: 1S/C14H16BNO/c16-11-12-17-15(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-10H,11-12,16H2
• InChI key: BLZVCIGGICSWIG-UHFFFAOYSA-N

Beschreibung

Application

• Investigating the Potentiation Effect of 2-APB on CRAC Channels: This study focused on the dual actions of 2-APB, which can potentiate and inhibit calcium influx via CRAC channels, aiming to unravel the underlying mechanisms (X Xu, SA Syed, T Xu - Biophysical Journal, 2015).
• Inhibitory Effects of 2-Aminoethoxydiphenyl Borate (2-APB) on Three KV1 Channel Currents: Explores 2-APB′s role as a multitarget compound with potential as a drug precursor, highlighting its effects on KV1 channel currents (W Zhao, et al. - Molecules, 2023).

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• hcodes: H315,H319,H335