539573

PKC Inhibitor Set

The PKC Inhibitor Set controls the biological activity of PKC. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

• Synonym(e): Protein Kinase C Inhibitor Set
• NACRES: NA.77
• UNSPSC Code: 12352200
• Form: solid
• Storage condition: OK to freeze, desiccated (hygroscopic), protect from light

Eigenschaften

• Quality Segment: 100
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, desiccated (hygroscopic), protect from light
• solubility: DMSO: soluble
• shipped in: ambient
• storage temp.: −20°C

Beschreibung

General description

Contains 250 µg of Bisindolylmaleimide I (Cat. No. 203290), 50 µg of Calphostin C, Cladosporium cladosporioides (Cat. No. 208725), 5 mg of Chelerythrine Chloride (Cat. No. 220285), 500 µg of Gö 6976 (Cat. No. 365250), 500 µg of Myristoylated Protein Kinase C Inhibitor 20-28, Cell-Permeable (Cat. No. 476480), and 1 mg of Ro-32-0432 (Cat. No. 557525). Supplied with a data sheet.

Inhibition of protein kinase C (PKC) is one of the most direct methods for investigating its role in cellular metabolism and tumorigenesis. Calbiochem^® brand is pleased to offer a convenient set of PKC inhibitors for your research needs. Supplied with a data sheet.

The PKC Inhibitor Set controls the biological activity of PKC. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Biochem/physiol Actions

Primary Target
PKC

Secondary Target
PKCα, PKCβ

Preparation Note

Following reconstitution, aliquot and freeze -20°C.

Other Notes

Eicholtz, T., et al. 1993. J. Biol. Chem.268, 1982.
Kleinschroth, J., et al. 1993. Bioorg. Med. Chem. Lett.3, 1959.
Martiny-Baron, G.M., et al. 1993. J. Biol. Chem.268, 9194.
Ward, N.E., and O′Brian, C.A. 1993. Biochemistry32, 11903.
Wilkinson, S.E., et al. 1993. Biochem. J.294, 335.
Barg, J., et al. 1992. J. Neurochem.59, 1145.
Gopalakrishna, R., et al. 1992. FEBS Lett.314, 149.
Bruns, R.F., et al. 1991. Biochem. Biophys. Res. Commun.176, 288.
Toullec, D., et al. 1991. J. Biol. Chem.266, 15771.
Herbert, J.M., et al. 1990. Biochem. Biophys. Res. Commun.1172, 993.
Tamaoki, T., et al. 1990. Biotechnology8, 732.
Kobayashi, E., et al. 1989. Biochem. Biophys. Res. Commun.159, 548.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Multiple Toxicity Values, refer to MSDS (O)

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 + H312 + H332,H315,H319,H335
• pcodes: P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Lagerklasse: 11 - Combustible Solids