345831

Galectin-1, Human, Recombinant, E. coli

• Synonym(e): Lactose-binding lectin 1, Beta-galactoside-binding lectin L-14-I, S-Lac lectin 1, Galaptin, 14 kDa lectin, HPL, HBL, MAPK activating protein MP12
• UNSPSC Code: 12352202
• Form: solid
• Assay: ≥98% (SDS-PAGE)

Eigenschaften

• assay: ≥98% (SDS-PAGE)
• Quality Segment: 100
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• solubility: water: 0.1-1 mg/mL
• shipped in: wet ice
• storage temp.: −20°C

Beschreibung

General description

Recombinant human galectin-1 expressed in and purified from E. coli. Galectins are a family of evolutionarily conserved animal lectins with affinity for β-galactosides that have homologous carbohydrate recognition domains (CRDs). Galectin-1 can induce apoptosis of activated T cells and leukemic T cell lines. It also binds to CD45 and inhibits its protein phosphatase activity.

Recombinant, human galectin-1 expressed in E. coli. Galectins are a family of evolutionarily conserved animal lectins with affinity for β-galactosides that have homologous carbohydrate recognition domains (CRDs). Galectin-1 can induce apoptosis of activated T cells and leukemic T cell lines. It also binds to CD45 and inhibits its protein phosphatase activity.

Physical form

Lyophilized from sterile-filtered 20 mM Tris-HCl, pH 7.5.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Diluted working solutions are stable for up to 1 week at 4°C or for up to 1 month at -20°C.

Further dilute into aqueous buffers as needed.

Other Notes

Rabinovich, A., et al. 2002. Trends Immunol.23, 313.
Rabinovich, A., et al. 2002. J. Leukoc. Biol.71, 741.
Hughes, R.C., et al. 2001. Biochimie.83, 667.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 1