Caspase-1-Inhibitor VI, Caspase-1 Inhibitor VI, Z-YVAD-FMK, is a potent, cell-permeable, and irreversible inhibitor of caspase-1, caspase-4, and caspase-5.
Ein potenter, zellpermeabler und irreversibler Inhibitor von Caspase-1 (ICE), Caspase-4 und Caspase-5.
Ein potenter, zellpermeabler und irreversibler Inhibitor von Caspase-1 (ICE).
Biochem/physiol Actions
Produkt konkurriert nicht mit ATP.
Reversibel: nein
Zellpermeabel: ja
Other Notes
Thornberry, N.A. und Lazebnik, Y. 1998. Science 281, 1312. Eldadah, B.A., et al. 1997. J. Neurosci. 17, 6105.
Z-Tyr-Val-Ala-Asp(OMe)-CH₂F*
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxizität: Standard-Handhabung (A)
Lagerklasse
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
Besitzen Sie dieses Produkt bereits?
In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.
Infection and immunity, 92(2), e0034223-e0034223 (2024-01-08)
Digital dermatitis (DD) is a skin disease in cattle characterized by painful inflammatory ulcerative lesions in the feet, mostly associated with local colonization by Treponema spp., including Treponema phagedenis. The reason why most DD lesions remain actively inflamed and progress
Macrophages are involved in various immune inflammatory disease conditions. This study aimed to investigate the role and mechanism of macrophages in regulating acute intestinal injury in neonatal necrotizing enterocolitis (NEC). CD68, nucleotide-binding oligomerization domain, leucine-rich repeat, and pyrin domain-containing 3
The Journal of allergy and clinical immunology, 144(2), 426-441 (2019-03-16)
House dust mite (HDM)-challenged Apoe-/- mice display enhanced airway hyperreactivity and mucous cell metaplasia. We sought to characterize the pathways that induce apolipoprotein E (APOE) expression by bronchoalveolar lavage fluid (BALF) macrophages from asthmatic subjects and identify how APOE regulates
Inflammatory macrophage to hepatocyte signals can be prevented by extracellular vesicle reprogramming.
Annals of clinical and translational neurology, 10(2), 246-265 (2022-12-28)
Neurodegeneration induced by inflammatory stress in multiple sclerosis (MS) leads to long-term neurological disabilities that are not amenable to current immunomodulatory therapies. Here, we report that neuronal downregulation of Splicing factor 3b subunit 2 (SF3B2), a component of U2 small
Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..