If Schiff's solution is not clear and colorless, it may indicate deterioration, especially if it is past expiration. However, if the bottle is within expiration, filing a complaint may be necessary. Various factors such as freezing, pH, and the presence of certain chemical components can affect the color and consistency of the solution.
1.02572
Schiff′s reagent Intense
for the detection of aldehyde and mucosubstances in microscopy
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NACRES:
NA.41
UNSPSC Code:
41116130
Quality Segment
form
liquid
IVD
for in vitro diagnostic use
pH
1.74 ( in H2O)
density
1.014 g/cm3 at 20 °C
storage temp.
20-25°C
General description
The Schiff′s reagent Intense - for the detection of aldehyde and mucosubstances in microscopy, is a ready-to-use solution used for human-medical cell diagnosis and serves the histological investigation of sample material of human origin, for example histological sections of e. g. the intestine or liver. This ready-to-use Schiff′s reagent Intense can be used to stain mucopolysaccharides in histological tissue specimens. The PAS (periodic acid schiff) reaction is one of the most frequently used chemical methods for the detection of aldehyde and mucosubstances in microscopy. In the PAS reaction, the histological specimen material is first treated with periodic acid, resulting in the oxidation of the 1,2-glycols into aldehyde groups. The addition of Schiff′s reagent (fuchsin-sulfuric acid) in the second step causes the aldehydes to react to form a brilliant red color. In the end result, the PAS reaction yields a specific color reaction with unsubstituted polysaccharides, neutral mucopolysaccharides, muco- and glycoproteins, and glyco- and phospholipids.
The PAS reaction can be further combined with the Alcian blue staining method to detect mucosubstances (glycosaminoglycans).
The 500 ml bottle is sufficient for 3000 stainings. This product is registered as IVD and CE marked. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.
The PAS reaction can be further combined with the Alcian blue staining method to detect mucosubstances (glycosaminoglycans).
The 500 ml bottle is sufficient for 3000 stainings. This product is registered as IVD and CE marked. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.
Application
For the detection of aldehydes, polysaccharides (glycogen), and mucosubstances (glycoproteins, glycolipids, mucins)
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Lagerklasse
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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Is it a concern if Schiff's reagent changes color to light pink upon exposure to air, even though it's a freshly opened bottle?
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