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Merck
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Dokumente

07-318

Sigma-Aldrich

Anti-TBX2 Antibody

serum, Upstate®

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

100

Antikörperform

serum

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Speziesreaktivität

mouse, human

Hersteller/Markenname

Upstate®

Methode(n)

immunoprecipitation (IP): suitable
western blot: suitable

Isotyp

IgG

NCBI-Hinterlegungsnummer

NM_005994

UniProt-Hinterlegungsnummer

Q13207

Versandbedingung

dry ice

Angaben zum Gen

human ... TBX2(6909)

Spezifität

TBX2

Immunogen

GST fusion protein corresponding to residues 554-702 of human TBX2

Anwendung

Detect TBX2 also known as T-box 2 with Anti-TBX2 Antibody (Rabbit Polyclonal Antibody), that has been demonstrated to work in IP & WB.

Qualität

routinely evaluated by immunoblot on RIPA lysates from MCF-7 human breast adenocarcinoma cells

Zielbeschreibung

74kDa

Physikalische Form

antiserum with 0.05% sodium azide before the addition of glycerol to 30%

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

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Juan Aparicio-Blanco et al.
Drug delivery and translational research (2024-05-13)
Brain drug delivery is severely hindered by the presence of the blood-brain barrier (BBB). Its functionality relies on the interactions of the brain endothelial cells with additional cellular constituents, including pericytes, astrocytes, neurons, or microglia. To boost brain drug delivery
J J Jacobs et al.
Nature genetics, 26(3), 291-299 (2000-11-04)
To identify new immortalizing genes with potential roles in tumorigenesis, we performed a genetic screen aimed to bypass the rapid and tight senescence arrest of primary fibroblasts deficient for the oncogene Bmi1. We identified the T-box member TBX2 as a
Timo H Lüdtke et al.
Respiratory research, 22(1), 85-85 (2021-03-19)
Tbx2 encodes a transcriptional repressor implicated in the development of numerous organs in mouse. During lung development TBX2 maintains the proliferation of mesenchymal progenitors, and hence, epithelial proliferation and branching morphogenesis. The pro-proliferative function was traced to direct repression of
Chen-Leng Cai et al.
Development (Cambridge, England), 132(10), 2475-2487 (2005-04-22)
Mutations in T-box genes are the cause of several congenital diseases and are implicated in cancer. Tbx20-null mice exhibit severely hypoplastic hearts and express Tbx2, which is normally restricted to outflow tract and atrioventricular canal, throughout the heart. Tbx20 mutant
K L Redmond et al.
Oncogene, 29(22), 3252-3262 (2010-03-30)
T-box 2 (TBX2) is a transcription factor involved in mammary development and is known to be overexpressed in a subset of aggressive breast cancers. TBX2 has previously been shown to repress growth control genes such as p14(ARF) and p21(WAF1/cip1). In
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