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Merck

05-538

Anti-phospho-Raf-1 (Ser338) Antibody

Upstate®, from mouse

Synonym(e):

Anti-CMD1NN, Anti-CRAF, Anti-NS5, Anti-Raf-1, Anti-c-Raf

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200 μG

€ 434,00

€ 434,00


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Über diesen Artikel

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
monoclonal
Species reactivity:
mouse
Application:
WB
Citations:
28

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Unterstützung erhalten

biological source

mouse

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

monoclonal

species reactivity

mouse

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

phosphorylation (pSer338)

Gene Information

human ... RAF1(5894)

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Dieser Artikel
07-453SAB4301241SAB1406366
biological source

mouse

biological source

rabbit

biological source

rabbit

biological source

mouse

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

clone

monoclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

species reactivity

mouse

species reactivity

human, rat, mouse

species reactivity

human

species reactivity

human

technique(s)

western blot: suitable

technique(s)

immunoprecipitation (IP): suitable, western blot: suitable

technique(s)

immunohistochemistry: 1:50-1:100, western blot: 1:500-1:1000 (Cell Lysate)

technique(s)

indirect immunofluorescence: suitable, western blot: 1 μg/mL

UniProt accession no.

P04049

UniProt accession no.

P15056

UniProt accession no.

P04049

UniProt accession no.

P04049

General description

74 kDa

Immunogen

Peptide corresponding to residues 333-345 of human Raf-1

Application

Anti-phospho-Raf-1 (Ser338) Antibody detects level of phospho-Raf-1 (Ser338) & has been published & validated for use in WB.
Research Category
Signaling
Research Sub Category
MAP Kinases

Biochem/physiol Actions

Recognizes Raf-1 phosphorylated at Serine 338.

Physical form

Format: Purified
Protein A Purified immunoglobulin in Protein A Purified immunoglobulin in 0.1M Tris-Glycine, 0.15M NaCl, 0.05% sodium azide, pH 7.4.
Protein G Purified

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Expressed in most tissue, lysates from 3T3/NIH cells stimulated with PDGF
routinely evaluated by immunoblot on RIPA lysates from 3T3/NIH cells stimulated with PDGF

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklasse

10 - Combustible liquids

wgk

WGK 1


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Antonia K Roseweir et al.
Journal of the National Cancer Institute, 110(6), 616-627 (2018-06-20)
Aromatase inhibitors improve disease-free survival compared with tamoxifen in postmenopausal women with hormone receptor-positive breast cancer. The Tamoxifen and Exemestane Adjuvant Multinational (TEAM) trial compared exemestane monotherapy with sequential therapy of tamoxifen followed by exemestane. The trial failed to show
Development of a highly reproducible three-dimensional organotypic model of the oral mucosa.
Anna Dongari-Bagtzoglou, Helena Kashleva
Nature Protocols null
Culture of Drosophila primary cells dissociated from gastrula embryos and their use in RNAi screening.
Bai J, Sepp KJ, Perrimon N
Nature Protocols null
F Peruzzi et al.
The Journal of biological chemistry, 276(28), 25990-25996 (2001-05-16)
The type 1 insulin-like growth factor receptor (IGF-IR) sends a strong anti-apoptotic signal by at least three different pathways. By using mutants of the IGF-IR, we showed that one of the pathways depends on residues of the IGF-IR (serines 1280--1283)
Yulei Zhao et al.
Nature, 599(7886), 679-683 (2021-11-12)
Inactive state-selective KRAS(G12C) inhibitors1-8 demonstrate a 30-40% response rate and result in approximately 6-month median progression-free survival in patients with lung cancer9. The genetic basis for resistance to these first-in-class mutant GTPase inhibitors remains under investigation. Here we evaluated matched pre-treatment

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