M-106

Mycophenolic acid solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• Empirische Formel (Hill-System): C₁₇H₂₀O₆
• CAS-Nummer: 24280-93-1
• Molekulargewicht: 320.34
• UNSPSC-Code: 41116107
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material
• Form: liquid
• Leistungsmerkmale: Snap-N-Spike^®/Snap-N-Shoot^®
• Verpackung: ampule of 1 mL
• Hersteller/Markenname: Cerilliant^®
• Konzentration: 1.0 mg/mL in acetonitrile
• Methode(n): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Anwendung(en): clinical testing
• Format: single component solution
• Lagertemp.: −70°C
• SMILES String: COc1c(C)c2COC(=O)c2c(O)c1C\C=C(/C)CCC(O)=O
• InChI: 1S/C17H20O6/c1-9(5-7-13(18)19)4-6-11-15(20)14-12(8-23-17(14)21)10(2)16(11)22-3/h4,20H,5-8H2,1-3H3,(H,18,19)/b9-4+
• InChIKey: HPNSFSBZBAHARI-RUDMXATFSA-N
• Angaben zum Gen: human ... IMPDH1(3614) , IMPDH2(3615)

Beschreibung

Allgemeine Beschreibung

Assayed in therapeutic drug monitoring to ensure patients remain within the drug′s therapeutic range, mycophenolic acid is an immunosuppressant drug and the active metabolite of the prodrug mycophenolate mofetil. This analytical standard is suitable for LC-MS/MS applications including therapeutic drug monitoring and other clinical or diagnostic applications.

Anwendung

• Targeted Inhibition in Gastrointestinal Toxicity: Mycophenolic acid is employed in targeted inhibition studies of gut bacterial β-glucuronidases to alleviate gastrointestinal toxicity caused by mycophenolate mofetil. This application is crucial for enhancing patient outcomes in immunosuppressive treatments, showcasing its value in pharmaceutical research (Xia et al., 2024).


• Synergistic Immunosuppression Therapy: The solution′s use in combination with low dose systemic immunosuppression to sustain vascularized composite allograft survival highlights its potential in transplant medicine. This research underscores the critical role of mycophenolic acid in developing effective immunosuppressive protocols (Feturi et al., 2024).


• Development of Genetic Markers: Mycophenolic acid′s biochemical properties are utilized in the development of genetic markers within Yarrowia lipolytica, demonstrating its importance in genetic engineering and biotechnological advancements (Zhu et al., 2024).


• Fungicidal Compound Discovery: The compound is used to derive fungicidal hydrazide lead compounds from sinapic acid and mycophenolic acid, illustrating its application in agricultural biochemistry and the development of new antimicrobial agents (Fang et al., 2023).

Angaben zur Herstellung

This product contains an ampule of 1 mL, at a concentration of 1.0 mg/mL in acetonitrile.

Rechtliche Hinweise

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS02,GHS07
• Signalwort: Danger
• H-Sätze: H225,H302 + H312 + H332,H319,H412
• P-Sätze: P210 - P273 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312
• Gefahreneinstufungen: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Flam. Liq. 2
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 2
• Flammpunkt (°F): 35.6 °F - closed cup
• Flammpunkt (°C): 2 °C - closed cup