880138P

DSPE-PEG(2000) Carboxy-NHS

Avanti Research^™ - A Croda Brand

• Synonym(e): DSPE-PEG(2000) Carboxy-NHS, 1,2-Distearoyl-sn-glycero-3-phosphoethanolamin-N-[carboxy(polyethylenglycol)-2000, NHS-Ester] (Natriumsalz)
• Empirische Formel (Hill-System): C₁₃₅H₂₆₀N₂NaO₅₇P
• CAS-Nummer: 2410279-87-5
• Molekulargewicht: 2877.45
• UNSPSC-Code: 12352211
• NACRES: NA.25

Eigenschaften

• Assay: >99% (TLC)
• Form: powder
• Verpackung: package of 1 × 10 mg
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand
• Anwendung(en): advanced drug delivery
• Lipid-Typ: polymerizable lipids
• Versandbedingung: dry ice
• Lagertemp.: −20°C

Beschreibung

Anwendung

• Enhanced detection of myeloma cells: DSPE-PEG(2000) Carboxy was used to create fluorescence labeled XT5 modified nano-capsules, enhancing the sensitivity of detecting myeloma cells. This application demonstrates its potential in biomedical diagnostics and targeted therapy (Norouz Dizaji et al., 2022).


• Improving drug encapsulation efficiency: The use of DSPE-PEG(2000) Carboxy in pre-formed liposomes for drug delivery showcases a method that significantly improves carboplatin encapsulation, highlighting its role in optimizing chemotherapeutic drug formulations (Wehbe et al., 2017).


• Targeted drug delivery for cardiovascular diseases: DSPE-PEG(2000) Carboxy was integral in the development of PEGylated-nanoliposomal formulations of clusterin, aimed at treating amyloidogenic light chain-induced endothelial dysfunction, underscoring its utility in targeted cardiovascular therapies (Guzman-Villanueva et al., 2018).

Verpackung

5-ml-Braunglasflasche mit Schraubkappe (880138P-25MG)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable