855375P

10:0 Lyso PC

1-decanoyl-2-hydroxy-sn-glycero-3-phosphocholine, powder

• Synonym(e): 1-decanoyl-sn-glycero-3-phosphocholine; PC(10:0/0:0)
• Empirische Formel (Hill-System): C₁₈H₃₈NO₇P
• CAS-Nummer: 22248-63-1
• Molekulargewicht: 411.47
• MDL-Nummer: MFCD00050433
• UNSPSC-Code: 51191904
• NACRES: NA.25

Eigenschaften

• Assay: >99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)
• Form: powder
• Verpackung: pkg of 1 × 25 mg (855375P-25mg); pkg of 1 × 500 mg (855375P-500mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand 855375P
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCC)=O
• InChI: 1S/C18H38NO7P/c1-5-6-7-8-9-10-11-12-18(21)24-15-17(20)16-26-27(22,23)25-14-13-19(2,3)4/h17,20H,5-16H2,1-4H3/t17-/m1/s1
• InChIKey: SECPDKKEUKDCPG-QGZVFWFLSA-N

Beschreibung

Allgemeine Beschreibung

Lyso-phosphatidylcholine (LPC) is a bioactive proinflammatory lipid secreted on pathological response.[1] It has a choline group at its polar head.[2]

Anwendung

10:0 Lyso PC has been used as an internal standard to quantify the most abundant lysophosphatidylcholine (LPC) species found in Trypanosoma cruzi samples.[3]

Biochem./physiol. Wirkung

Lysophosphatidylcholine (LPC) alters various biological functions in different cell-types, such as endothelial cells, smooth muscle cells, monocytes, macrophages and T-cells. It is associated with atherosclerosis and inflammatory diseases. LPC activates many second messengers including, protein kinase C, extracellular-signal-regulated kinases and protein tyrosine kinases.[1]

Verpackung

20 mL Clear Glass Screw Cap Vial (855375P-500mg)

5 mL Clear Glass Sealed Ampule (855375P-25mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable