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F2456

Fluorescein (freie Säure)

Dye content 95%, Powder

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Größe/SKUVerfügbarkeitPreis
2.5 g
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€ 38,90
100 g
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€ 75,40
500 g
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€ 301,00

Über diesen Artikel

Empirische Formel (Hill-System):
C20H12O5
CAS-Nummer:
Molekulargewicht:
332.31
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
Colour Index Number:
45350:1
EC Number:
219-031-8
MDL number:
Beilstein/REAXYS Number:
94324

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Produktname

Fluorescein (freie Säure), Dye content 95 %

form

powder

Quality Segment

composition

Dye content, 95%

technique(s)

titration: suitable

color

orange to red-brown

mp

320 °C (lit.)

λmax

496 nm

ε (extinction coefficient)

≥12000 at 282-286 nm, ≥39000 at 236-240 nm, ≥70000 at 488-492 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Oc1ccc2c(Oc3cc(O)ccc3C24OC(=O)c5ccccc45)c1

InChI

1S/C20H12O5/c21-11-5-7-15-17(9-11)24-18-10-12(22)6-8-16(18)20(15)14-4-2-1-3-13(14)19(23)25-20/h1-10,21-22H

InChI key

GNBHRKFJIUUOQI-UHFFFAOYSA-N

General description

Fluorescein (free acid, CI 45350) is a xanthene dye. Fluorescein (free acid) molecule can be divided into two parts. One part contains xanthene moiety which acts as fluorophore and the other part of the molecule bears benzene moiety which is the fluorescence-controlling moiety.

Application

Fluorescein (free acid) has been used as a staining agent in retinal imaging.
Fluorescein (free acid) is widely used as a fluorescent stain and trace for many living cells and tissue applications. It is also suitable as a marker for the study of motility of bile canaliculi. Some of the clinical applications are evaluating the ocular surface and delineation of brain regions lacking a blood-brain barrier to permit accurate surgical resection of malignant glioma. Fluorescein angiography helps investigate changes in retinal blood supply. Fluorescein also plays a role as a physiological tracer to characterize the salmon′s intestinal permeability (Schep et al., 1998), and for the fluorophotometric measurement of aqueous humor flow. It is widely employed as a quantum yield standard.

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Dieser Artikel
Y0000796127700446955
Fluorescein European Pharmacopoeia (EP) Reference Standard

Y0000796

Fluorescein

Fluorescein United States Pharmacopeia (USP) Reference Standard

USP

1277004

Fluorescein

description

Dye content 95 %

description

European Pharmacopoeia (EP) Reference Standard

description

United States Pharmacopeia (USP) Reference Standard

description

free acid

technique(s)

titration: suitable

technique(s)

-

technique(s)

-

technique(s)

titration: suitable

color

orange to red-brown

color

-

color

-

color

red

form

powder

form

-

form

-

form

powder or crystals

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

-

Quality Level

200

Quality Level

-

Quality Level

-

Quality Level

100

composition

Dye content, 95%

composition

-

composition

-

composition

-


Piktogramme

Exclamation mark

Signalwort

Warning

Gefahrencodes

Sicherheitshinweise

Hazard Classifications

Eye Irrit. 2

Lagerklasse

11 - Combustible Solids

Was ist los?

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

PSA (Persönliche Schutzausrüstung)

Eyeshields, Gloves, type N95 (US)



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Questions

Reviews

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  1. Brown University Providence RI
    • Review 1
    • Votes 4
    1 out of 5 stars.

    new product not working when the old one did

    This product didn't work. i was wondering if we could be a credit or reimbursed?
    We have used this in the last (lot# BCCD8787) and it worked but the new one we got (BCCH4248) didn't.

    Helpful?

    1. Response from Merck KGaA:

      Thank you for taking the time to leave a review. We are sorry to hear that your experience did not meet expectations. Our Customer Service team has reached out to you in effort to resolve this issue. We apologize for any inconvenience this may have caused.