E18859

Cyanameisensäure-ethylester

≥95%

• Synonym(e): 2-Ethoxy-2-oxoacetonitrile, Cyanocarbonyloxyethane, Cyanoformic acid ethyl ester, Ethoxycarbonyl cyanide, Ethyl carbonocyanidate
• Lineare Formel: NCCO₂C₂H₅
• CAS-Nummer: 623-49-4
• Molekulargewicht: 99.09
• UNSPSC Code: 12352100
• NACRES: NA.22
• PubChem Substance ID: 24894440
• EC Number: 210-797-9
• Beilstein/REAXYS Number: 635955
• MDL number: MFCD00001836
• Assay: ≥95%
• Form: liquid

Eigenschaften

• Quality Segment: 100
• assay: ≥95%
• form: liquid
• refractive index: n20/D 1.381 (lit.)
• bp: 115-116 °C (lit.)
• density: 1.003 g/mL at 25 °C (lit.)
• functional group: ester, nitrile
• SMILES string: CCOC(=O)C#N
• InChI: 1S/C4H5NO2/c1-2-7-4(6)3-5/h2H2,1H3
• InChI key: MSMGXWFHBSCQFB-UHFFFAOYSA-N

Beschreibung

Application

Ethyl cyanoformate is a general cyanating agent. It can be used in the nucleophilic addition of cyanide to carbonyl compounds, oxidative cyanation of tertiary amines and in the synthesis of β-cyano-substituted acrylates from alkynes.

Ethyl cyanoformate can be used as a cyanide source for the cyanation of:

• Activated olefins in the presence of a titanium catalyst.
• Carbonyl compounds catalyzed by 4-dimethylaminopyridine (DMAP) to yield corresponding cyanohydrin carbonates under metal-free and solvent-free conditions.
• Aldehydes and 2,2,2-trifluoroacetophenone catalyzed by N-heterocyclic carbene (NHC) to yield corresponding cyanohydrins ethyl carbonates.

Sicherheitshinweise

• Piktogramme: GHS02,GHS05
• Signalwort: Danger
• Gefahrencodes: H226,H314
• Sicherheitshinweise: P210 - P280 - P303 + P361 + P353 - P305 + P351 + P338 + P310
• Hazard Classifications: Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B
• Lagerklasse: 3 - Flammable liquids
• Was ist los?: WGK 3
• Flammpunkt (°F): 75.2 °F - closed cup
• Flammpunkt (°C): 24 °C - closed cup
• PSA (Persönliche Schutzausrüstung): Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter