The Properties section of the product page includes the description "form liquid". This applies to all package sizes of the product.
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Wichtige Dokumente
B103608
γ-Butyrolacton
γ-Butyrolactone
ReagentPlus®, ≥99%
Synonym(e):
γ-Hydroxybuttersäure-Lacton, 4-Butyrolacton, GBL
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About This Item
Empirische Formel (Hill-System):
C4H6O2
CAS-Nummer:
Molekulargewicht:
86.09
Beilstein:
105248
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:
NACRES:
NA.22
Preise und Verfügbarkeit sind derzeit nicht verfügbar.
Empfohlene Produkte
Dampfdichte
3 (vs air)
Qualitätsniveau
Dampfdruck
1.5 mmHg ( 20 °C)
Produktlinie
ReagentPlus®
Assay
≥99%
Form
liquid
Selbstzündungstemp.
851 °F
Expl.-Gr.
16 %
Brechungsindex
n20/D 1.436 (lit.)
bp
204-205 °C (lit.)
mp (Schmelzpunkt)
−45 °C (lit.)
Dichte
1.12 g/mL at 25 °C (lit.)
SMILES String
O=C1CCCO1
InChI
1S/C4H6O2/c5-4-2-1-3-6-4/h1-3H2
InChIKey
YEJRWHAVMIAJKC-UHFFFAOYSA-N
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Verwandte Kategorien
Anwendung
Biochem./physiol. Wirkung
Vorstufe von γ-Hydroxybuttersäure (GHB), blockiert die Dopaminfreisetzung.
Vorstufe von γ-Hydroxybuttersäure (GHB). Es blockiert die Freisetzung von Dopamin durch die Hemmung der Impulsleitung in dopaminergen Neuronen. Die Vorbehandlung mit γ-Butyrolacton ermöglicht den Nachweis einer autorezeptorvermittelten Dopaminausschüttung.
Rechtliche Hinweise
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
Signalwort
Danger
H-Sätze
Gefahreneinstufungen
Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3
Zielorgane
Central nervous system
Lagerklassenschlüssel
10 - Combustible liquids
WGK
WGK 1
Flammpunkt (°F)
208.4 °F - closed cup
Flammpunkt (°C)
98 °C - closed cup
Persönliche Schutzausrüstung
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
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A novel series of (3-pyridylmethyl)benzoquinone derivatives was molecular designed and synthesized for the dual purpose of inhibiting thromboxane A2 and leukotriene biosynthesis enzymes and scavenging active oxygen species (AOS). They were evaluated for inhibition of TXA2 synthase, inhibition of 5-lipoxygenase
Jagan N Thupari et al.
Proceedings of the National Academy of Sciences of the United States of America, 99(14), 9498-9502 (2002-06-13)
C75, a known inhibitor of fatty acid synthase is postulated to cause significant weight loss through decreased hypothalamic neuropeptide Y (NPY) production. Peripherally, C75, an alpha-methylene-gamma-butyrolactone, reduces adipose tissue and fatty liver, despite high levels of malonyl-CoA. To investigate this
Michael Seitz et al.
Current opinion in chemical biology, 9(3), 285-292 (2005-06-09)
Natural products containing a gamma-butyrolactone ring are abundant in nature; however, few general synthetic approaches to their stereoselective synthesis with broad structural variety are known. In this article, recent developments towards mono- and polycyclic gamma-butyrolactone natural products and analogs are
Zheng-Yuan Su et al.
Chemical research in toxicology, 26(3), 477-485 (2013-02-28)
Cancer development has been linked to epigenetic modifications of cancer oncogenes and tumor suppressor genes; in advanced metastatic cancers, severe epigenetic modifications are present. We previously demonstrated that the progression of prostate tumors in TRAMP mice is associated with methylation
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Your product name γ-Butyrolactone with the number B103608 has an option for 500grams so I just wanted to double check that it’s in liquid form because the places I bought from before had there listings in liters. Thank you for your time.
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How can I determine the shelf life / expiration / retest date of this product?
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If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdfHelpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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