This product consists of PEG-3000-coated, amine-functionalized fluorescent nanodiamonds with amine groups presented on the PEG layer, not directly on the nanodiamond surface via a short linker. The PEG spacer improves accessibility and reduces steric hindrance. According to technical documentation, these surface amine groups are suitable for direct functionalization using NHS-activated biotin reagents, supporting their use in microscopy reference and biotin–streptavidin–based applications.
Please see the links below to review additional information that may be helpful:
Fluorescent Nanodiamonds for Bioimaging
https://www.sigmaaldrich.com/US/en/technical-documents/technical-article/materials-science-and-engineering/biosensors-and-imaging/fluorescent-nanodiamonds
Fluorescent Nanodiamond Particles: Properties and Applications
https://www.sigmaaldrich.com/US/en/technical-documents/technical-article/materials-science-and-engineering/biosensors-and-imaging/fluorescent-nanodiamond-particles