900862

(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol

• Synonym(e): Hydroxyl diazirine TMS-alkyne, Probe building block
• Empirische Formel (Hill-System): C₁₄H₁₅F₃N₂OSi
• CAS-Nummer: 2187374-13-4
• Molekulargewicht: 312.36
• UNSPSC Code: 12352200
• NACRES: NA.22
• Assay: ≥95%
• Form: powder or crystals

Eigenschaften

• assay: ≥95%
• form: powder or crystals
• storage temp.: −20°C
• SMILES string: OCC1=CC=C(C2(N=N2)C(F)(F)F)C=C1C#C[Si](C)(C)C

Beschreibung

Application

(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Other Notes

Technology Spotlight: Trifunctional Probe Building Blocks

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable