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Merck

765538

Sigma-Aldrich

Gold nanoparticles

30 nm diameter, carboxylic acid functionalized, PEG 3000 coated, OD 50, dispersion in H2O

Synonym(e):

Gold nanoparticles COOH functionalized, Au NP COOH, Gold Colloid

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About This Item

UNSPSC-Code:
12162002
NACRES:
NA.23

Materialien

PEG 3000

Form

dispersion in H2O
nanoparticles

Verpackung

poly bottle of 1 mL

OD

50

Durchmesser

30 nm

pH-Wert

6.0-8.0 (25 °C)

Löslichkeit

water: miscible

Dichte

1.00 g/cm3

λmax

525 nm

Funktionelle Gruppe

carboxylic acid

Lagertemp.

2-8°C

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Allgemeine Beschreibung

Carboxylic acid functionalized GNPs forms conjugates with various protein molecules due to the electrostatic attraction between negatively charged carboxylate groups and positively charged amino groups of protein.

Anwendung

Gold nanoparticles 30 nm diameter, carboxylic acid functionalized, PEG 3000 coated, OD 50, dispersion in H2O can be potentially used in the development of biosensors, cancer-cell imaging, drug delivery, and photothermal therapy.
AuNPs may also be used in the immobilization of antibodies to improve the sensitivity of optical fiber sensors for the screening of COVID-19. It can also be deposited on the titanium electrode for the formation of a miniaturized device for the electrochemical detection of DNA hybridization.
The carboxylic acid group binds with various proteins and are used in targeted drug delivery and gene therapy.
Functionalized Particles have been extensively used to study cellular uptake of nanoparticles and targeted drug delivery.

Leistungsmerkmale und Vorteile

Decreases the cytotoxicity and increases efficiency of GNPs in targeted drug delivery. PEG increases the stability of the nanoparticles and prevents agglomeration.

Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Optical Fiber Sensors for Rapid Screening of COVID-19
Nag P, et al.
Transactions of the Indian National Academy of Engineering, 6, 1-4 (2020)
Nóra Adányi et al.
Food chemistry, 267, 10-14 (2018-06-24)
Mycotoxins, present in a wide range of food and feed commodities, are toxic secondary metabolites produced by a number of different fungi. Certain mycotoxins do not readily degrade at high temperatures, therefore are resistant to food processing, and consequently are
Size-dependent in vivo toxicity of PEG-coated gold nanoparticles
Zhang X, et al.
International journal of nanomedicine, 6, 2071-2071 (2011)
Nishima Wangoo et al.
Journal of colloid and interface science, 323(2), 247-254 (2008-05-20)
We report a novel strategy for the synthesis of aqueous stable, carboxylated gold nanoparticles (GNPs) by using glutamic acid as the reducing agent. The ratio of chloroaurate ions, AuCl(-)(4) to glutamic acid was optimized in the reaction medium to obtain
Functionalized gold nanoparticles and their biomedical applications
Tiwari, P. M., Vig, K., Dennis, V. A., & Singh, S. R.
Nanomaterials, 1(1), 31-63 (2011)

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