670359

Acetylthiomethyl-diphenylphosphin-Boran-Komplex

≥98.0%

• Synonym(e): (T-4)-[S-[(Diphenylphosphino-κP)methyl] ethanethioate]trihydroboron
• Empirische Formel (Hill-System): C₁₅H₁₈BOPS
• CAS-Nummer: 446822-71-5
• Molekulargewicht: 288.15
• UNSPSC Code: 12352200
• PubChem Substance ID: 329760266
• NACRES: NA.22
• eCl@ss: 32150313

Eigenschaften

• assay: ≥98.0%
• form: solid
• reaction suitability: reaction type: click chemistry, reagent type: ligand; reaction type: Staudinger Reaction
• mp: 52-55 °C
• functional group: phosphine
• storage temp.: 2-8°C
• SMILES string: B.CC(=O)SCP(c1ccccc1)c2ccccc2
• InChI: 1S/C15H15OPS.BH3/c1-13(16)18-12-17(14-8-4-2-5-9-14)15-10-6-3-7-11-15;/h2-11H,12H2,1H3;1H3
• InChI key: MXPNVFCCEGQGEN-UHFFFAOYSA-N

Beschreibung

Application

• Traceless Staudinger ligation reagent with borane protecting group.
• The borane group stabilizes the phosphine against oxidation and can be easily removed with mild basic or acidic conditions to yield the active phosphine.
• After reaction with an azide, the phosphine is eliminated in the presence of water to yield a native amide bond.
• Used in the synthesis of cyclic peptides.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Legal Information

Sold under license for research and development purposes only. US Patent 6,974,884 and related patents apply

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H315,H319,H335
• Sicherheitshinweise: P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): dust mask type N95 (US), Eyeshields, Gloves