520322

2-Cyanobenzylzinkbromid -Lösung

0.5 M in THF

• Lineare Formel: NCC₆H₄CH₂ZnBr
• CAS-Nummer: 199465-66-2
• Molekulargewicht: 261.43
• MDL-Nummer: MFCD01311397
• UNSPSC-Code: 12352103
• PubChem Substanz-ID: 24874105
• NACRES: NA.22

Eigenschaften

• Konzentration: 0.5 M in THF
• Dichte: 0.993 g/mL at 25 °C
• Funktionelle Gruppe: nitrile
• Lagertemp.: 2-8°C
• SMILES String: Br[Zn]Cc1ccccc1C#N
• InChI: 1S/C8H6N.BrH.Zn/c1-7-4-2-3-5-8(7)6-9;;/h2-5H,1H2;1H;/q;;+1/p-1
• InChIKey: LQRNYQAXNZETFP-UHFFFAOYSA-M

Beschreibung

Anwendung

2-Cyanobenzylzinc bromide can be used as a reactant:

• In the metal-catalyzed Negishi cross-coupling reactions to prepare aryl or heteroaryl derivatives via carbon-carbon bond formation.
• To synthesize 4-(2-Cyanobenzyl)-3′-(trifluoromethyl)biphenyl by reacting with aryl nonaflate in the presence of Pd(dba)₂ as a catalyst.
• To prepare 2-[(2-cyanophenyl)methyl] benzamide by treating with 2-iodobenzamide using a nickel catalyst.

Rechtliche Hinweise

Product of Rieke^® Metals, Inc.

Sicherheitshinweise

• Piktogramme: GHS02,GHS08,GHS07
• Signalwort: Danger
• H-Sätze: H225,H319,H335,H336,H351
• P-Sätze: P202 - P210 - P233 - P240 - P305 + P351 + P338 - P308 + P313
• Gefahreneinstufungen: Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• Zielorgane: Central nervous system, Respiratory system
• Zusätzliche Gefahrenhinweise: EUH014,EUH019
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): 1.4 °F - closed cup
• Flammpunkt (°C): -17 °C - closed cup