476951

(2S,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutan

99%

• Synonym(e): tert.-Butyl-[S-(R*,R*)]-(−)-(1-oxiranyl-2-phenylethyl)-carbamat
• Empirische Formel (Hill-System): C₁₅H₂₁NO₃
• CAS-Nummer: 98737-29-2
• Molekulargewicht: 263.33
• MDL-Nummer: MFCD02258997
• UNSPSC-Code: 12352005
• PubChem Substanz-ID: 24871318
• NACRES: NA.22

Eigenschaften

• Assay: 99%
• Optische Aktivität: [α]23/D −7°, c = 0.6 in methanol
• mp (Schmelzpunkt): 125-127 °C (lit.)
• SMILES String: [H][C@@]1(CO1)[C@H](Cc2ccccc2)NC(=O)OC(C)(C)C
• InChI: 1S/C15H21NO3/c1-15(2,3)19-14(17)16-12(13-10-18-13)9-11-7-5-4-6-8-11/h4-8,12-13H,9-10H2,1-3H3,(H,16,17)/t12-,13+/m0/s1
• InChIKey: NVPOUMXZERMIJK-QWHCGFSZSA-N

Beschreibung

Anwendung

(2S,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane can be used as a reactant to prepare:

• Hydroxyethyl urea peptidomimetics as potent γ-secretase inhibitors.
• Arylsufonamide derivatives.
• Peptidomimetic β-secretase inhibitors incorporating hydroxyethylamine isosteres.

Sicherheitshinweise

• Piktogramme: GHS09
• Signalwort: Warning
• H-Sätze: H410
• P-Sätze: P273 - P501
• Gefahreneinstufungen: Aquatic Acute 1 - Aquatic Chronic 1
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable