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467804

Sigma-Aldrich

Hydroxylamin -Lösung

50 wt. % in H2O, 99.999%

Synonym(e):

HDA

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€ 108,00

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10 ML
€ 52,60
50 ML
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About This Item

Lineare Formel:
NH2OH
CAS-Nummer:
Molekulargewicht:
33.03
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352116
PubChem Substanz-ID:
NACRES:
NA.22

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Qualitätsniveau

Assay

99.999%

Konzentration

50 wt. % in H2O

bp

107 °C

Dichte

1.078 g/mL at 25 °C

SMILES String

NO

InChI

1S/H3NO/c1-2/h2H,1H2

InChIKey

AVXURJPOCDRRFD-UHFFFAOYSA-N

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Allgemeine Beschreibung

Hydroxylamine solution is widely used as a reducing agent and antioxidant in organic synthesis, polymer industry and water treatment.[1]

Anwendung

Reaktionsmittel für die Herstellung von:
  • Pro-Drug für den kardiovaskulären Wirkstoff Nω-Hydroxy-L-Arginin (NOHA, Stickstoffoxidvorläufer)
  • Hydroxyaminoguanidine als Wirkstoffe gegen Krebs
  • Nichtsteroidale 2,3-Dihydrochinolinglukokortikoid-Rezeptoragonisten mit reduzierter Phosphoenolpyruvat-Carboxykinase(PEPCK)-Transaktivierung
  • Carboxamid-Derivate von Ofloxacin mit verbesserten antimikrobiellen Eigenschaften
  • Analoga von Coumarin-basierten Inhibitoren des TNF-α konvertierenden Enzyms (TACE)
  • HIV-Integrase-Inhibitoren
Hydroxylamine solution (NH2OH) can be used as a reactant for the preparation of:
  • Primary amides from aldehydes catalyzed by an arene–ruthenium(II) complex.[2]
  • Hydroxyaminoguanidines and carboxamide derivatives of ofloxacin for biological studies.[3][4]
  • Fe3O4/Au (GoldMag) nanoparticles for antibody immobilization.[5]

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 4 Oral - Aquatic Acute 1 - Carc. 2 - Desen. Expl. 4 - Eye Dam. 1 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 - STOT SE 3

Zielorgane

Blood, Respiratory system

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 3

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

The synthesis of GoldMag nano-particles and their application for antibody immobilization
Cui Y, et al.
Biomedical Microdevices, 7(2), 153-156 (2005)
Ruthenium-catalyzed one-pot synthesis of primary amides from aldehydes in water
Garcia-Alvarez R, et al.
Royal Society of Chemistry Advances, 3(17), 5889-5894 (2013)
N-Hydroxy-N′-aminoguanidines as anti-cancer lead molecule: QSAR, synthesis and biological evaluation
Basu A, et al.
Bioorganic & Medicinal Chemistry Letters, 21(11), 3324-3328 (2011)
Using hydroxylamine as a reducer to prepare N-doped graphene hydrogels used in high-performance energy storage
Chang, Yunzhen and Han, et al.
Journal of Power Sources, 238, 492-500 (2013)
Synthesis, characterization and biological activity of a series of carboxamide derivatives of ofloxacin
Arayne MS, et al.
Archives of Pharmacal Research, 33(12), 1901-1909 (2010)

Questions

1–3 of 3 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. Please provide the molarity for Product 467804?

    1 answer
    1. The molarity of a 50% solution for Product 467804 would be 15.1M. This is calculated based on the fact that 1M is equivalent to 33.03 g in 1L

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