375772

1-Acetyl-3-indolcarboxaldehyd

98%

• Synonym(e): N-Acetylindol-3-carboxaldehyde, NSC 61289
• Empirische Formel (Hill-System): C₁₁H₉NO₂
• CAS-Nummer: 22948-94-3
• Molekulargewicht: 187.19
• NACRES: NA.22
• PubChem Substance ID: 24863403
• UNSPSC Code: 12352100
• EC Number: 245-347-0
• MDL number: MFCD00039691
• Assay: 98%

Eigenschaften

• Quality Segment: 100
• assay: 98%
• mp: 165 °C (lit.)
• functional group: aldehyde
• SMILES string: CC(=O)n1cc(C=O)c2ccccc12
• InChI: 1S/C11H9NO2/c1-8(14)12-6-9(7-13)10-4-2-3-5-11(10)12/h2-7H,1H3
• InChI key: LCJLFGSKHBDOAY-UHFFFAOYSA-N

Beschreibung

General description

1-Acetyl-3-indolecarboxaldehyde participates in the preparation and characterization of three RNA-specific fluorescent probes (E36, E144 and F22), useful in live cell imaging.

Application

Reactant for synthesis of α-ketoamides as inhibitors of Dengue virus protease with antiviral activity in cell-culture
Reactant for preparation of homoallylic amines as antimicrobial agents
Reactant for preparation of pyrrole-based hydrazones as potential tuberculostatics
Reactant for synthesis of neoechinulin A and derivatives
Reactant for synthesis of substituted (Z)-2-(N-benzylindol-3-ylmethylene)quinuclidin-3-one and (Z)-(±)-2-(N-benzylindol-3-ylmethylene)quinuclidin-3-ol derivatives as potent thermal sensitizing agents
Reactant for preparation of RNA-specific live cell imaging probes E36, E144 and F22

1-Acetyl-3-indolecarboxaldehyde may be used to prepare the thiosemicarbazones, via condensation reaction.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H315,H319,H335
• Sicherheitshinweise: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): dust mask type N95 (US), Eyeshields, Gloves