359866

Isocyanmethylphosphonsäure-diethylester

97%

• Synonym(e): Diethylisocyanomethylphosphonat, Isocyanmethanphosphonsäure-diethylester
• Lineare Formel: CNCH₂P(O)(OC₂H₅)₂
• CAS-Nummer: 41003-94-5
• Molekulargewicht: 177.14
• Beilstein: 4674920
• MDL-Nummer: MFCD00042951
• UNSPSC-Code: 12352108
• PubChem Substanz-ID: 24862114
• NACRES: NA.22

Eigenschaften

• Assay: 97%
• Form: liquid
• Eignung der Reaktion: reaction type: C-C Bond Formation
• Brechungsindex: n20/D 1.433 (lit.)
• bp: 84-87 °C/0.1 mmHg (lit.)
• Dichte: 1.105 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: amine; isonitrile; phosphonate
• Lagertemp.: 2-8°C
• SMILES String: CCOP(=O)(C[N+]#[C-])OCC
• InChI: 1S/C6H12NO3P/c1-4-9-11(8,6-7-3)10-5-2/h4-6H2,1-2H3
• InChIKey: ICURVXBGGDVHDT-UHFFFAOYSA-N

Beschreibung

Anwendung

Reactant for:

• Copper-catalyzed cycloaddition reactions
• Preparation of orally bioavailable diamide prodrugs that lower glucose in diabetic animals through inhibition of fructose-1,6-bisphosphatase
• Synthesis of sterol analogs as antifungal agents against plant pathogens
• Asymmetric synthesis of steroidal 2,5-diketopiperazines prepared via isocyanide chemistry based on stereoselective Ugi four component condensation and subsequent cyclocondensation reactions
• The Passerini reaction

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302 + H312 + H332,H315,H319,H335
• P-Sätze: P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): 235.4 °F - closed cup
• Flammpunkt (°C): 113 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type ABEK (EN14387) respirator filter