324124

2-Chlor-1,3,2-benzodioxaphosphorin-4-on

95%

• Synonym(e): Salicyl-chlorphosphit
• Empirische Formel (Hill-System): C₇H₄ClO₃P
• CAS-Nummer: 5381-99-7
• Molekulargewicht: 202.53
• Beilstein: 1311951
• MDL-Nummer: MFCD00013353
• UNSPSC-Code: 12352005
• PubChem Substanz-ID: 24859425
• NACRES: NA.22

Eigenschaften

• Assay: 95%
• Form: solid
• Eignung der Reaktion: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand
• bp: 127-128 °C/11 mmHg (lit.)
• mp (Schmelzpunkt): 36-40 °C (lit.)
• Funktionelle Gruppe: phosphine
• Lagertemp.: 2-8°C
• SMILES String: ClP1OC(=O)c2ccccc2O1
• InChI: 1S/C7H4ClO3P/c8-12-10-6-4-2-1-3-5(6)7(9)11-12/h1-4H
• InChIKey: BVOITXUNGDUXRW-UHFFFAOYSA-N

Beschreibung

Anwendung

2-Chloro-1,3,2-benzodioxaphosphorin-4-one is used as a reagent:

• In the phosphorylation and phosphitylation of alcohols.
• In the formation of H-phosphonates which are commonly utilized in the synthesis of nucleotides.
• To synthesize nucleoside triphosphates by treating with acyl protected nucleoside.

Sicherheitshinweise

• Piktogramme: GHS05
• Signalwort: Danger
• H-Sätze: H314
• P-Sätze: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Gefahreneinstufungen: Eye Dam. 1 - Skin Corr. 1B
• Zusätzliche Gefahrenhinweise: EUH014
• Lagerklassenschlüssel: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): 235.4 °F - closed cup
• Flammpunkt (°C): 113 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges