303461

(R)-(+)-β-Citronellol

95%

• Synonym(e): (+)-β-Citronellol, (R)-3,7-Dimethyl-6-octen-1-ol
• Lineare Formel: (CH₃)₂C=CHCH₂CH₂CH(CH₃)CH₂CH₂OH
• CAS-Nummer: 1117-61-9
• Molekulargewicht: 156.27
• Beilstein: 1721506
• EG-Nummer: 214-250-5
• MDL-Nummer: MFCD00063215
• UNSPSC-Code: 12352002
• PubChem Substanz-ID: 24858125
• NACRES: NA.22

Eigenschaften

• Dampfdruck: ~0.02 mmHg ( 25 °C)
• Assay: 95%
• Form: liquid
• Optische Aktivität: [α]19/D +5.3°, neat
• Brechungsindex: n20/D 1.456 (lit.)
• bp: 112-113 °C/12 mmHg (lit.)
• Dichte: 0.857 g/mL at 25 °C (lit.)
• SMILES String: C[C@@H](CCO)CC\C=C(\C)C
• InChI: 1S/C10H20O/c1-9(2)5-4-6-10(3)7-8-11/h5,10-11H,4,6-8H2,1-3H3/t10-/m1/s1
• InChIKey: QMVPMAAFGQKVCJ-SNVBAGLBSA-N

Beschreibung

Anwendung

(R)-(+)-β-Citronellol can be used to prepare:

• (R)-(+)-β-citronellyl acetate by treating with vinyl acetate via trans esterification reaction using immobilized Rhizomucor miehei lipase as biocatalyst.
• (R)-(+)-citronellal and (R)-(+)-citronellic acid by the oxidation reaction.
• Citronellol aziridine by treating with 2,2,2-trichloroethoxysulfonamide by intermolecular olefin aziridination.

It can also be used as a starting material for the synthesis of (+)-integerrinecic acid lactone.

(R)-(+)-β-Citronellol can undergo:

• Oxidation to form (R)-(+)-citronellal, an antifungal agent and (R)-(+)-citronellic acid.
• Intermolecular olefin aziridination with 2,2,2-trichloroethoxysulfonamide to form citronellol aziridine for ring-opening reactions.
• Series of reactions to form α2δ-ligands for treating generalized anxiety disorder and insomnia.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): 212.0 °F - closed cup
• Flammpunkt (°C): 100 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type ABEK (EN14387) respirator filter