20023

O-tert.-Butylhydroxylamin -hydrochlorid

≥99.0% (AT)

• Synonym(e): 2-Aminooxy-2-methylpropane hydrochloride, O-(1,1-Dimethylethyl)hydroxylamine hydrochloride, tert-Butoxyamine hydrochloride
• Lineare Formel: (CH₃)₃CONH₂ · HCl
• CAS-Nummer: 39684-28-1
• Molekulargewicht: 125.60
• UNSPSC Code: 12352100
• NACRES: NA.22
• PubChem Substance ID: 57647770
• EC Number: 254-590-1
• Beilstein/REAXYS Number: 3668106
• MDL number: MFCD00043272
• eCl@ss: 32160703
• Assay: ≥99.0% (AT)
• Form: solid

Eigenschaften

• Quality Segment: 200
• assay: ≥99.0% (AT)
• form: solid
• mp: ~155 °C (dec.)
• solubility: H₂O: soluble 0.5 g/10 mL
• SMILES string: Cl.CC(C)(C)ON
• InChI: 1S/C4H11NO.ClH/c1-4(2,3)6-5;/h5H2,1-3H3;1H
• InChI key: ZBDXGNXNXXPKJI-UHFFFAOYSA-N

Beschreibung

Application

O-tert-Butylhydroxylamine hydrochloride was used in the synthesis of N-methyl-O-tert-butylhydroxylamine hydrochloride. It was also used in the preparation of N-tert-butoxyamino acids as substrates for the unambiguous synthesis of N-hydroxy peptides.

Reactant involved in synthesis of biologically active molecules including:

• CGS 25966 derivatives for use as MMP inhibitors
• Imidazolidinedione derivatives for use as antimalarial treatments
• Pyrimidine ribonucleotide analogs as P2Y6 receptor agonists
• Rab proteins for isoprenylation and geranylgeranylation inhibition

Reactant involved in:

• Synthesis of N-(arylethyl)-O-tert-butylhydroxamates for use as Weinreb amide equivalents
• Double allylic alkylation of indole-2-hydroxamates
• SN2 substitution reactions at amide nitrogens
• Photocycloaddition to C=N bonds for synthesis of 1,3-diazepines

Sicherheitshinweise

• Piktogramme: GHS02
• Signalwort: Warning
• Gefahrencodes: H228
• Sicherheitshinweise: P210
• Hazard Classifications: Flam. Sol. 2
• Lagerklasse: 4.1B - Flammable solid hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): Eyeshields, Gloves, type P3 (EN 143) respirator cartridges