162434

AM-ex-OL

97%

• Synonym(e): 4-Chlor-2-phenylchinazolin
• Empirische Formel (Hill-System): C₁₄H₉ClN₂
• CAS-Nummer: 6484-25-9
• Molekulargewicht: 240.69
• EG-Nummer: 229-346-2
• MDL-Nummer: MFCD00006713
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24849981
• NACRES: NA.22

Eigenschaften

• Assay: 97%
• Form: liquid
• mp (Schmelzpunkt): 124-126 °C (lit.)
• SMILES String: Clc1nc(nc2ccccc12)-c3ccccc3
• InChI: 1S/C14H9ClN2/c15-13-11-8-4-5-9-12(11)16-14(17-13)10-6-2-1-3-7-10/h1-9H
• InChIKey: OBHKONRNYCDRKM-UHFFFAOYSA-N

Beschreibung

Anwendung

4-Chloro-2-phenylquinazoline was used in synthesis of axially chiral quinazoline-containing phosphinamine ligand, N,N,2-triphenylquinazolin-4-amine, sulfanyl and sulfinylbenzodiazines. It was used as reagent for the conversion of phenols to anilines.

Reactant involved in the synthesis of biologically active molecules including:

• Nitrotriazole amines or nitroimidazole amines for use as antitrypanosomal activity and mammalian cytotoxicity
• Quinazoline-containing piperazinylpyrimidine derivatives with antitumor activity
• Quinazoline substituted cyclopentane as HCV NS3/4A protease inhibitors
• Quinazolines with antibacterial and antitumor activity
• Aurora inhibitor MK-0457

Reactant involved in Suzuki-Miyaura cross-coupling and catalyst-free / base-free water promoted nucleophilic aromatic substitution

Rechtliche Hinweise

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable