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1,3-Diphenyl-2-propenon
≥98.0% (GC)
Synonym(e):
Benzalacetophenon, Chalkon
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About This Item
Lineare Formel:
C6H5CH=CHCOC6H5
CAS-Nummer:
Molekulargewicht:
208.26
Beilstein:
1210466
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:
NACRES:
NA.22
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Assay
≥98.0% (GC)
Löslichkeit
dioxane: soluble 1 g/10 mL, clear, colorless
Funktionelle Gruppe
ketone
phenyl
SMILES String
O=C(\C=C\c1ccccc1)c2ccccc2
InChI
1S/C15H12O/c16-15(14-9-5-2-6-10-14)12-11-13-7-3-1-4-8-13/h1-12H/b12-11+
InChIKey
DQFBYFPFKXHELB-VAWYXSNFSA-N
Angaben zum Gen
rat ... Ar(24208)
Anwendung
1,3-Diphenyl-2-propenone was used in the preparation of pharmacologically-interesting heterocyclic systems like pyrazolines and pyrimidines.
Biochem./physiol. Wirkung
1,3-Diphenyl-2-propenone (chalcone) inhibits the proliferation of human breast cancer cell lines, MCF-7 and MDA-MB-231 by inducing apoptosis and blocking cell cycle progression in the G2/M phase. It is an inhibitor of Plasmodium falciparum cyclin-dependent protein kinases.
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Persönliche Schutzausrüstung
dust mask type N95 (US), Eyeshields, Gloves
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