10926

N-Hydroxycarbamidsäure-(9-fluorenylmethyl)-ester

≥99.0%

• Synonym(e): N-(9-Fluorenylmethoxycarbonyl)-hydroxylamin, N-Fmoc-hydroxylamin
• Empirische Formel (Hill-System): C₁₅H₁₃NO₃
• CAS-Nummer: 190656-01-0
• Molekulargewicht: 255.27
• Beilstein: 7712144
• MDL-Nummer: MFCD01862911
• UNSPSC-Code: 12352005
• PubChem Substanz-ID: 57646856

Eigenschaften

• Assay: ≥99.0%
• mp (Schmelzpunkt): 164.5 °C (lit.)
• Anwendung(en): peptide synthesis
• SMILES String: ONC(=O)OCC1c2ccccc2-c3ccccc13
• InChI: 1S/C15H13NO3/c17-15(16-18)19-9-14-12-7-3-1-5-10(12)11-6-2-4-8-13(11)14/h1-8,14,18H,9H2,(H,16,17)
• InChIKey: HHNJBGORPSTJDX-UHFFFAOYSA-N

Beschreibung

Anwendung

9-Fluorenylmethyl N-hydroxycarbamate (Fmoc-NHOH) can be used as a reactant to prepare:

• N-Fmoc-aminooxy-2-chlorotrityl polystyrene, a solid-phase resin used to produce hydroxamic acids and peptidyl hydroxamic acids.
• 9-Fluorenylmethyl nosyloxycarbamate (Fmoc-NHONs) by reacting with nosyl chloride.

Sonstige Hinweise

Building block for the solid-phase synthesis of (peptide) hydroxamic acids on chlorotrityl resin

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves