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PIK3R1

phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

Synonyme:
AGM7, GRB1, p85, p85-ALPHA
Spezies:
Human PIK3R1 (5295), Mouse Pik3r1 (18708), Rat Pik3r1 (25513), domestic guinea pig Pik3r1 (100730242), domestic cat PIK3R1 (100271864), cow PIK3R1 (282307), sheep PIK3R1 (101121455), chicken PIK3R1 (427171), Zebrafish pik3r1 (557176), dog PIK3R1 (487235)
UniProtKB-ID:
P27986, B3KT19, D3DWA0, E7EX19, Q15747, Q4VBZ7, Q53EM6, Q8IXA2
Gen-ID:
  • Human(5295) Summary: Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
  • Mouse(18708) phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
  • Rat(25513) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  • domestic guinea pig(100730242) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  • domestic cat(100271864) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  • cow(282307) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  • sheep(101121455) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  • chicken(427171) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  • Zebrafish(557176) phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)
  • dog(487235) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
05-212
Anti-PI3 Kinase Antibody, p85, N-SH3, clone AB6, clone AB6, Upstate®, from mouse,
Speziesreaktivität
human, mouse, rat
Anwendung
immunocytochemistry
immunoprecipitation (IP)
western blot
SAB4504315
Anti-phospho-PI3-kinase p85-α (pTyr607) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunohistochemistry
western blot
SAB5500162
Anti-PI3K P85 antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP62, affinity isolated antibody,
Speziesreaktivität
bovine, frog, human, mouse, rat
Anwendung
flow cytometry
immunohistochemistry
SAB4504314
Anti-phospho-PI3-kinase p85-α/γ (pTyr467/199) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunofluorescence
western blot
ABS1856
Anti-PI3-Kinase-Antikörper, p85, from rabbit, purified by affinity chromatography,
Speziesreaktivität
bovine, human, mouse, rat, rhesus monkey
Anwendung
immunoprecipitation (IP)
western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
W1628
Wortmannin aus Penicillium funiculosum, from Penicillium funiculosum, ≥98% (HPLC and TLC),
Spezies
human
W3144
Wortmannin, Ready Made Solution, from Penicillium funiculosum, ≥95% (HPLC),
Spezies
human
D2926
Diphenyleniodoniumchlorid, ≥98%,
Spezies
mouse, human
PZ0235
PF-04691502, ≥98% (HPLC),
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
EHU151811
MISSION® esiRNA, targeting human PIK3R1,
Spezies
human
EMU187151
MISSION® esiRNA, targeting mouse Pik3r1,
Spezies
mouse